Human Gene ALX1 (ENST00000316824.4) from GENCODE V44
Description: Homo sapiens ALX homeobox 1 (ALX1), mRNA. (from RefSeq NM_006982) RefSeq Summary (NM_006982): The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000316824.4 Gencode Gene: ENSG00000180318.4 Transcript (Including UTRs) Position: hg38 chr12:85,280,220-85,301,784 Size: 21,565 Total Exon Count: 4 Strand: + Coding Region Position: hg38 chr12:85,280,262-85,301,475 Size: 21,214 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.