Human Gene ACAD10 (ENST00000313698.9) from GENCODE V44
Description: Homo sapiens acyl-CoA dehydrogenase family member 10 (ACAD10), transcript variant 2, mRNA. (from RefSeq NM_025247) RefSeq Summary (NM_025247): This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008]. Gencode Transcript: ENST00000313698.9 Gencode Gene: ENSG00000111271.15 Transcript (Including UTRs) Position: hg38 chr12:111,686,053-111,757,099 Size: 71,047 Total Exon Count: 21 Strand: + Coding Region Position: hg38 chr12:111,692,710-111,756,473 Size: 63,764 Coding Exon Count: 20
ID:ACD10_HUMAN DESCRIPTION: RecName: Full=Acyl-CoA dehydrogenase family member 10; Short=ACAD-10; EC=1.3.99.-; FUNCTION: Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA. CATALYTIC ACTIVITY: Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. COFACTOR: FAD (By similarity). TISSUE SPECIFICITY: Widely expressed with highest expression in fetal brain, followed by heart, muscle, kidney and adult brain. Expression levels varying from isoform to isoform. SIMILARITY: Belongs to the acyl-CoA dehydrogenase family. SEQUENCE CAUTION: Sequence=AAH15056.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6JQN1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
