ID:GCP3_HUMAN DESCRIPTION: RecName: Full=Gamma-tubulin complex component 3; Short=GCP-3; Short=hGCP3; AltName: Full=Gamma-ring complex protein 104 kDa; Short=h104p; Short=hGrip104; AltName: Full=Spindle pole body protein Spc98 homolog; Short=hSpc98; FUNCTION: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. SUBUNIT: Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. Interacts with CDK5RAP2; the interaction is leading to centrosomal localization of TUBGCP3 and CDK5RAP2. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, centrosome. TISSUE SPECIFICITY: Ubiquitously expressed. SIMILARITY: Belongs to the TUBGCP family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96CW5
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
