Human Gene OR4K2 (ENST00000298642.2) from GENCODE V44
Description: Odorant receptor (Potential). (from UniProt Q8NGD2) RefSeq Summary (NM_001005501): Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## Gencode Transcript: ENST00000298642.2 Gencode Gene: ENSG00000165762.3 Transcript (Including UTRs) Position: hg38 chr14:19,876,232-19,877,309 Size: 1,078 Total Exon Count: 1 Strand: + Coding Region Position: hg38 chr14:19,876,268-19,877,212 Size: 945 Coding Exon Count: 1
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8NGD2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007165 signal transduction GO:0007186 G-protein coupled receptor signaling pathway GO:0007608 sensory perception of smell GO:0050896 response to stimulus GO:0050907 detection of chemical stimulus involved in sensory perception GO:0050911 detection of chemical stimulus involved in sensory perception of smell
US Server
