Human Gene RIN3 (ENST00000216487.12) from GENCODE V44
Description: Homo sapiens Ras and Rab interactor 3 (RIN3), transcript variant 1, mRNA. (from RefSeq NM_024832) RefSeq Summary (NM_024832): This protein encoded by this gene is a member of the RIN family of Ras interaction-interference proteins, which are binding partners to the RAB5 small GTPases. The protein functions as a guanine nucleotide exchange for RAB5B and RAB31. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]. Gencode Transcript: ENST00000216487.12 Gencode Gene: ENSG00000100599.16 Transcript (Including UTRs) Position: hg38 chr14:92,513,781-92,688,994 Size: 175,214 Total Exon Count: 10 Strand: + Coding Region Position: hg38 chr14:92,513,933-92,688,252 Size: 174,320 Coding Exon Count: 10
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8TB24
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.