Human Gene CCDC32 (ENST00000558750.5) from GENCODE V44
  Description: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9BV29-1; Sequence=Displayed; Name=2; IsoId=Q9BV29-2; Sequence=VSP_027485; Note=No experimental confirmation available; Name=3; IsoId=Q9BV29-3; Sequence=VSP_027486, VSP_027487; Note=No experimental confirmation available; (from UniProt Q9BV29)
Gencode Transcript: ENST00000558750.5
Gencode Gene: ENSG00000128891.17
Transcript (Including UTRs)
   Position: hg38 chr15:40,553,942-40,564,980 Size: 11,039 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg38 chr15:40,553,971-40,564,780 Size: 10,810 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr15:40,553,942-40,564,980)mRNA (may differ from genome)Protein (194 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGencodeGeneCardsHPRDLynx
MalacardsMGIneXtProtPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: CO057_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C15orf57; AltName: Full=Protein CCDC32;
SEQUENCE CAUTION: Sequence=CAD89911.1; Type=Erroneous initiation;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 7.11 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 121.55 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -80.90200-0.405 Picture PostScript Text
3' UTR 0.00290.000 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9BV29
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding


-  Descriptions from all associated GenBank mRNAs
  BC012189 - Homo sapiens cDNA clone IMAGE:4644158, partial cds.
AK098781 - Homo sapiens cDNA FLJ25915 fis, clone CBR04830.
AL832032 - Homo sapiens mRNA; cDNA DKFZp451P134 (from clone DKFZp451P134).
BC001673 - Homo sapiens chromosome 15 open reading frame 57, mRNA (cDNA clone MGC:2530 IMAGE:2823236), complete cds.
AK092214 - Homo sapiens cDNA FLJ34895 fis, clone NT2NE2018176.
AX747411 - Sequence 936 from Patent EP1308459.
JD049626 - Sequence 30650 from Patent EP1572962.
AK312842 - Homo sapiens cDNA, FLJ93284.
CU674824 - Synthetic construct Homo sapiens gateway clone IMAGE:100022377 5' read CCDC32 mRNA.
HQ447606 - Synthetic construct Homo sapiens clone IMAGE:100070951; CCSB013389_02 coiled-coil domain containing 32 (CCDC32) gene, encodes complete protein.
KJ895122 - Synthetic construct Homo sapiens clone ccsbBroadEn_04516 C15orf57 gene, encodes complete protein.
AK293079 - Homo sapiens cDNA FLJ77717 complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: A8KAL4, AK092214, C15orf57, CO057_HUMAN, ENST00000558750.1, ENST00000558750.2, ENST00000558750.3, ENST00000558750.4, Q86TC4, Q8N788, Q8NAR7, Q9BV29, uc001zma.1, uc001zma.2, uc001zma.3
UCSC ID: ENST00000558750.5
RefSeq Accession: NM_001080791
Protein: Q9BV29 (aka CO057_HUMAN)
CCDS: CCDS10060.1, CCDS42022.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.