Human Gene RCN2 (ENST00000394885.8) from GENCODE V44
Description: Homo sapiens reticulocalbin 2 (RCN2), transcript variant 1, mRNA. (from RefSeq NM_002902) RefSeq Summary (NM_002902): The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]. Gencode Transcript: ENST00000394885.8 Gencode Gene: ENSG00000117906.14 Transcript (Including UTRs) Position: hg38 chr15:76,931,749-76,954,393 Size: 22,645 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr15:76,931,842-76,949,222 Size: 17,381 Coding Exon Count: 7
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q14257
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.