Human Gene SPATA2L (ENST00000289805.10) from GENCODE V44
  Description: Homo sapiens spermatogenesis associated 2 like (SPATA2L), mRNA. (from RefSeq NM_152339)
Gencode Transcript: ENST00000289805.10
Gencode Gene: ENSG00000158792.16
Transcript (Including UTRs)
   Position: hg38 chr16:89,696,357-89,701,705 Size: 5,349 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg38 chr16:89,697,334-89,701,232 Size: 3,899 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr16:89,696,357-89,701,705)mRNA (may differ from genome)Protein (424 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCHPRDLynxMGIneXtProtPubMed
UniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: SPA2L_HUMAN
DESCRIPTION: RecName: Full=Spermatogenesis-associated protein 2-like protein; Short=SPATA2-like protein;
SIMILARITY: Belongs to the SPATA2 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.97 RPKM in Pituitary
Total median expression: 90.67 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -39.7079-0.503 Picture PostScript Text
3' UTR -483.70977-0.495 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8IUW3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  BC053588 - Homo sapiens spermatogenesis associated 2-like, mRNA (cDNA clone MGC:61628 IMAGE:5245683), complete cds.
AF070574 - Homo sapiens clone 24819 mRNA sequence.
BC039608 - Homo sapiens spermatogenesis associated 2-like, mRNA (cDNA clone MGC:48943 IMAGE:5248678), complete cds.
BC027606 - Homo sapiens spermatogenesis associated 2-like, mRNA (cDNA clone IMAGE:4827501), complete cds.
AK127372 - Homo sapiens cDNA FLJ45448 fis, clone BRSTN2000312.
JD128716 - Sequence 109740 from Patent EP1572962.
JD055561 - Sequence 36585 from Patent EP1572962.
JD390476 - Sequence 371500 from Patent EP1572962.
JD317445 - Sequence 298469 from Patent EP1572962.
JD217587 - Sequence 198611 from Patent EP1572962.
JD469059 - Sequence 450083 from Patent EP1572962.
JD483465 - Sequence 464489 from Patent EP1572962.
JD063983 - Sequence 45007 from Patent EP1572962.
JD425661 - Sequence 406685 from Patent EP1572962.
KJ903706 - Synthetic construct Homo sapiens clone ccsbBroadEn_13100 SPATA2L gene, encodes complete protein.
JD181227 - Sequence 162251 from Patent EP1572962.
JD148974 - Sequence 129998 from Patent EP1572962.
JD408887 - Sequence 389911 from Patent EP1572962.
JD151153 - Sequence 132177 from Patent EP1572962.
JD323235 - Sequence 304259 from Patent EP1572962.
JD137042 - Sequence 118066 from Patent EP1572962.
JD446041 - Sequence 427065 from Patent EP1572962.
JD117335 - Sequence 98359 from Patent EP1572962.
JD210219 - Sequence 191243 from Patent EP1572962.
HQ448530 - Synthetic construct Homo sapiens clone IMAGE:100071965; CCSB010313_01 spermatogenesis associated 2-like (SPATA2L) gene, encodes complete protein.
KJ900085 - Synthetic construct Homo sapiens clone ccsbBroadEn_09479 SPATA2L gene, encodes complete protein.
CU691740 - Synthetic construct Homo sapiens gateway clone IMAGE:100020886 5' read SPATA2L mRNA.
LF212253 - JP 2014500723-A/19756: Polycomb-Associated Non-Coding RNAs.
MA447830 - JP 2018138019-A/19756: Polycomb-Associated Non-Coding RNAs.
DQ598173 - Homo sapiens piRNA piR-36239, complete sequence.
JD394455 - Sequence 375479 from Patent EP1572962.
JD204743 - Sequence 185767 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C16orf76, D3DX85, ENST00000289805.1, ENST00000289805.2, ENST00000289805.3, ENST00000289805.4, ENST00000289805.5, ENST00000289805.6, ENST00000289805.7, ENST00000289805.8, ENST00000289805.9, NM_152339, Q8IUW3, Q8NHV3, SPA2L_HUMAN, uc002foj.1, uc002foj.2, uc002foj.3, uc002foj.4, uc002foj.5
UCSC ID: ENST00000289805.10
RefSeq Accession: NM_152339
Protein: Q8IUW3 (aka SPA2L_HUMAN)
CCDS: CCDS10985.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.