Human Gene SOCS7 (ENST00000612932.6) from GENCODE V44
  Description: Homo sapiens suppressor of cytokine signaling 7 (SOCS7), mRNA. (from RefSeq NM_014598)
Gencode Transcript: ENST00000612932.6
Gencode Gene: ENSG00000274211.6
Transcript (Including UTRs)
   Position: hg38 chr17:38,351,844-38,405,593 Size: 53,750 Total Exon Count: 10 Strand: +
Coding Region
   Position: hg38 chr17:38,352,053-38,395,968 Size: 43,916 Coding Exon Count: 9 

Page IndexSequence and LinksPrimersCTDMicroarray ExpressionRNA Structure
Other SpeciesmRNA DescriptionsPathwaysOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:38,351,844-38,405,593)mRNA (may differ from genome)Protein (645 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCHPRDLynxMalacardsMGIOMIM
PubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -131.90209-0.631 Picture PostScript Text
3' UTR -2216.306111-0.363 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD Ensembl  
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

-  Descriptions from all associated GenBank mRNAs
  BC121030 - Homo sapiens cDNA clone IMAGE:40117482.
BC121031 - Homo sapiens cDNA clone IMAGE:40117484.
BC128607 - Homo sapiens suppressor of cytokine signaling 7, mRNA (cDNA clone IMAGE:40117485), partial cds.
BC167822 - Synthetic construct Homo sapiens clone IMAGE:100068212, MGC:195829 suppressor of cytokine signaling 7 (SOCS7) mRNA, encodes complete protein.
AB005216 - Homo sapiens mRNA for Nck, Ash and phospholipase C gamma-binding protein NAP4, partial cds.
JD471507 - Sequence 452531 from Patent EP1572962.
JD095499 - Sequence 76523 from Patent EP1572962.
JD442390 - Sequence 423414 from Patent EP1572962.
JD424406 - Sequence 405430 from Patent EP1572962.
JD200502 - Sequence 181526 from Patent EP1572962.
DQ593634 - Homo sapiens piRNA piR-33746, complete sequence.
DQ590571 - Homo sapiens piRNA piR-57683, complete sequence.
JD027222 - Sequence 8246 from Patent EP1572962.
JD034867 - Sequence 15891 from Patent EP1572962.
JD024722 - Sequence 5746 from Patent EP1572962.
JD028954 - Sequence 9978 from Patent EP1572962.
JD411494 - Sequence 392518 from Patent EP1572962.
JD538477 - Sequence 519501 from Patent EP1572962.
JD148926 - Sequence 129950 from Patent EP1572962.
JD068796 - Sequence 49820 from Patent EP1572962.
JD360746 - Sequence 341770 from Patent EP1572962.
JD231363 - Sequence 212387 from Patent EP1572962.
JD273260 - Sequence 254284 from Patent EP1572962.
JD427518 - Sequence 408542 from Patent EP1572962.
JD277244 - Sequence 258268 from Patent EP1572962.
JD490296 - Sequence 471320 from Patent EP1572962.
JD184840 - Sequence 165864 from Patent EP1572962.
JD469198 - Sequence 450222 from Patent EP1572962.
JD225523 - Sequence 206547 from Patent EP1572962.
JD339744 - Sequence 320768 from Patent EP1572962.
JD205529 - Sequence 186553 from Patent EP1572962.
DQ588938 - Homo sapiens piRNA piR-56050, complete sequence.
AK094338 - Homo sapiens cDNA FLJ37019 fis, clone BRACE2010669.
JD054812 - Sequence 35836 from Patent EP1572962.
JD492288 - Sequence 473312 from Patent EP1572962.
DQ581547 - Homo sapiens piRNA piR-49659, complete sequence.
JD221514 - Sequence 202538 from Patent EP1572962.
JD368729 - Sequence 349753 from Patent EP1572962.
JD279793 - Sequence 260817 from Patent EP1572962.
JD110702 - Sequence 91726 from Patent EP1572962.
JD325271 - Sequence 306295 from Patent EP1572962.
DQ586216 - Homo sapiens piRNA piR-53328, complete sequence.
DQ596256 - Homo sapiens piRNA piR-34322, complete sequence.
DQ590975 - Homo sapiens piRNA piR-58087, complete sequence.
JD155297 - Sequence 136321 from Patent EP1572962.
JD216586 - Sequence 197610 from Patent EP1572962.
JD090584 - Sequence 71608 from Patent EP1572962.
JD224515 - Sequence 205539 from Patent EP1572962.
JD380329 - Sequence 361353 from Patent EP1572962.
JD252241 - Sequence 233265 from Patent EP1572962.
JD534340 - Sequence 515364 from Patent EP1572962.
JD486439 - Sequence 467463 from Patent EP1572962.
JD319089 - Sequence 300113 from Patent EP1572962.
JD294818 - Sequence 275842 from Patent EP1572962.
DQ590519 - Homo sapiens piRNA piR-57631, complete sequence.
JD128064 - Sequence 109088 from Patent EP1572962.
JD340516 - Sequence 321540 from Patent EP1572962.
JD076711 - Sequence 57735 from Patent EP1572962.
JD364256 - Sequence 345280 from Patent EP1572962.
JD365369 - Sequence 346393 from Patent EP1572962.
JD547806 - Sequence 528830 from Patent EP1572962.
JD227958 - Sequence 208982 from Patent EP1572962.
JD130911 - Sequence 111935 from Patent EP1572962.
JD487103 - Sequence 468127 from Patent EP1572962.
JD203229 - Sequence 184253 from Patent EP1572962.
JD455762 - Sequence 436786 from Patent EP1572962.
JD432275 - Sequence 413299 from Patent EP1572962.
JD041334 - Sequence 22358 from Patent EP1572962.
JD321080 - Sequence 302104 from Patent EP1572962.
JD388255 - Sequence 369279 from Patent EP1572962.
JD138441 - Sequence 119465 from Patent EP1572962.
JD092345 - Sequence 73369 from Patent EP1572962.
JD060031 - Sequence 41055 from Patent EP1572962.
DQ593570 - Homo sapiens piRNA piR-33682, complete sequence.
JD025283 - Sequence 6307 from Patent EP1572962.
JD031941 - Sequence 12965 from Patent EP1572962.
DQ596336 - Homo sapiens piRNA piR-34402, complete sequence.
DQ579266 - Homo sapiens piRNA piR-47378, complete sequence.
JD026907 - Sequence 7931 from Patent EP1572962.
JD030546 - Sequence 11570 from Patent EP1572962.
DQ592094 - Homo sapiens piRNA piR-59206, complete sequence.
DQ592095 - Homo sapiens piRNA piR-59207, complete sequence.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa04630 - Jak-STAT signaling pathway

-  Other Names for This Gene
  Alternate Gene Symbols: A0A5F9YLF9, ENST00000612932.1, ENST00000612932.2, ENST00000612932.3, ENST00000612932.4, ENST00000612932.5, NM_014598, uc002hqa.1, uc002hqa.2, uc002hqa.3, uc002hqa.4, uc002hqa.5
UCSC ID: ENST00000612932.6
RefSeq Accession: NM_014598

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.