Human Gene PRR15L (uc002imp.4) Description and Page Index
  Description: Homo sapiens proline rich 15-like (PRR15L), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr17:46,029,334-46,035,243 Size: 5,910 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr17:46,030,289-46,030,600 Size: 312 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:46,029,334-46,035,243)mRNA (may differ from genome)Protein (103 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerGeneCardsGeneNetworkH-INV
HGNCHPRDLynxMGIneXtProtPubMed
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: PR15L_HUMAN
DESCRIPTION: RecName: Full=Proline-rich protein 15-like protein; AltName: Full=Protein ATAD4;
SIMILARITY: Belongs to the PRR15 family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 67.75 RPKM in Stomach
Total median expression: 406.28 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -89.04250-0.356 Picture PostScript Text
3' UTR -357.81955-0.375 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15321 - ATPase family AAA domain containing 4

ModBase Predicted Comparative 3D Structure on Q9BU68
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC002865 - Homo sapiens ATPase family, AAA domain containing 4, mRNA (cDNA clone MGC:11242 IMAGE:3939938), complete cds.
AK309589 - Homo sapiens cDNA, FLJ99630.
JD183798 - Sequence 164822 from Patent EP1572962.
JD147768 - Sequence 128792 from Patent EP1572962.
JD162593 - Sequence 143617 from Patent EP1572962.
JD096577 - Sequence 77601 from Patent EP1572962.
JD162784 - Sequence 143808 from Patent EP1572962.
JD355153 - Sequence 336177 from Patent EP1572962.
JD355469 - Sequence 336493 from Patent EP1572962.
JD383170 - Sequence 364194 from Patent EP1572962.
JD216339 - Sequence 197363 from Patent EP1572962.
JD355471 - Sequence 336495 from Patent EP1572962.
JD397628 - Sequence 378652 from Patent EP1572962.
JD077879 - Sequence 58903 from Patent EP1572962.
JD109214 - Sequence 90238 from Patent EP1572962.
JD237320 - Sequence 218344 from Patent EP1572962.
JD277132 - Sequence 258156 from Patent EP1572962.
JD348508 - Sequence 329532 from Patent EP1572962.
JD467388 - Sequence 448412 from Patent EP1572962.
JD530393 - Sequence 511417 from Patent EP1572962.
JD209649 - Sequence 190673 from Patent EP1572962.
HM005470 - Homo sapiens clone HTL-T-157 testicular tissue protein Li 157 mRNA, complete cds.
JD262951 - Sequence 243975 from Patent EP1572962.
JD353445 - Sequence 334469 from Patent EP1572962.
JD145769 - Sequence 126793 from Patent EP1572962.
JD245948 - Sequence 226972 from Patent EP1572962.
HQ448299 - Synthetic construct Homo sapiens clone IMAGE:100071714; CCSB004397_02 ATPase family, AAA domain containing 4 (ATAD4) gene, encodes complete protein.
KJ894670 - Synthetic construct Homo sapiens clone ccsbBroadEn_04064 PRR15L gene, encodes complete protein.
JD167927 - Sequence 148951 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ATAD4, D3DTU0, NM_024320, NP_077296, PR15L_HUMAN, Q9BU68, uc002imp.3
UCSC ID: uc002imp.4
RefSeq Accession: NM_024320
Protein: Q9BU68 (aka PR15L_HUMAN)
CCDS: CCDS11523.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_024320.3
exon count: 2CDS single in 3' UTR: no RNA size: 1530
ORF size: 312CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 824.00frame shift in genome: no % Coverage: 99.15
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.