Human Gene RAB27B (ENST00000262094.10) from GENCODE V44
Description: Homo sapiens RAB27B, member RAS oncogene family (RAB27B), transcript variant 1, mRNA. (from RefSeq NM_004163) RefSeq Summary (NM_004163): Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000262094.10 Gencode Gene: ENSG00000041353.10 Transcript (Including UTRs) Position: hg38 chr18:54,828,477-54,895,516 Size: 67,040 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr18:54,877,586-54,889,413 Size: 11,828 Coding Exon Count: 5
ID:RB27B_HUMAN DESCRIPTION: RecName: Full=Ras-related protein Rab-27B; AltName: Full=C25KG; FUNCTION: May be involved in targeting uroplakins to urothelial apical membranes (By similarity). SUBUNIT: Binds SYTL4 and MYRIP. Interacts with SYTL2 (By similarity). SUBCELLULAR LOCATION: Membrane; Lipid-anchor. TISSUE SPECIFICITY: Expressed primarily in testis. SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O00194
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.