Human Gene KRI1 (ENST00000312962.12) from GENCODE V44
Description: Homo sapiens KRI1 homolog (KRI1), mRNA. (from RefSeq NM_023008) RefSeq Summary (NM_023008): This gene overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. [provided by RefSeq, Jul 2008]. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation. Gencode Transcript: ENST00000312962.12 Gencode Gene: ENSG00000129347.21 Transcript (Including UTRs) Position: hg38 chr19:10,553,085-10,566,010 Size: 12,926 Total Exon Count: 19 Strand: - Coding Region Position: hg38 chr19:10,553,951-10,565,999 Size: 12,049 Coding Exon Count: 19
ID:KRI1_HUMAN DESCRIPTION: RecName: Full=Protein KRI1 homolog; PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: Belongs to the KRI1 family. SEQUENCE CAUTION: Sequence=BAB15278.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF05178 - KRI1-like family PF12936 - KRI1-like family C-terminal
ModBase Predicted Comparative 3D Structure on Q8N9T8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)