Human Gene CABP5 (ENST00000293255.3) from GENCODE V44
Description: Homo sapiens calcium binding protein 5 (CABP5), mRNA. (from RefSeq NM_019855) RefSeq Summary (NM_019855): The product of this gene belongs to a subfamily of calcium binding proteins, which share similarity to calmodulin. Calcium binding proteins are an important component of calcium mediated cellular signal transduction. Expression of this gene is retina-specific. The mouse homolog of this protein has been shown to express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. The specific function of this gene is unknown. [provided by RefSeq, Oct 2009]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000293255.3 Gencode Gene: ENSG00000105507.3 Transcript (Including UTRs) Position: hg38 chr19:48,029,383-48,044,079 Size: 14,697 Total Exon Count: 6 Strand: - Coding Region Position: hg38 chr19:48,030,557-48,043,922 Size: 13,366 Coding Exon Count: 6
ID:CABP5_HUMAN DESCRIPTION: RecName: Full=Calcium-binding protein 5; Short=CaBP5; FUNCTION: Inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. Involved in the transmission of light signals (By similarity). SUBUNIT: Interacts with CACNA1C (via C-terminal CDB motif) in a calcium-dependent manner (By similarity). SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Retina. SIMILARITY: Contains 4 EF-hand domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NP86
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
