Human Gene HS1BP3 (ENST00000304031.8) from GENCODE V44
Description: Homo sapiens HCLS1 binding protein 3 (HS1BP3), mRNA. (from RefSeq NM_022460) RefSeq Summary (NM_022460): The protein encoded by this gene shares similarity with mouse Hs1bp3, an Hcls1/Hs1-interacting protein that may be involved in lymphocyte activation. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000304031.8 Gencode Gene: ENSG00000118960.13 Transcript (Including UTRs) Position: hg38 chr2:20,617,818-20,651,098 Size: 33,281 Total Exon Count: 7 Strand: - Coding Region Position: hg38 chr2:20,618,987-20,651,063 Size: 32,077 Coding Exon Count: 7
ID:H1BP3_HUMAN DESCRIPTION: RecName: Full=HCLS1-binding protein 3; AltName: Full=HS1-binding protein 3; Short=HSP1BP-3; FUNCTION: May be a modulator of IL-2 signaling (By similarity). SUBUNIT: Binds HCLS1. Interacts with the SH3 domain of HCLS1 in vitro (By similarity). SIMILARITY: Contains 1 PX (phox homology) domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q53T59
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.