Human Gene CLIP4 (ENST00000401605.5) from GENCODE V44
Description: Homo sapiens CAP-Gly domain containing linker protein family member 4 (CLIP4), transcript variant 3, mRNA. (from RefSeq NM_001287528)
Gencode Transcript: ENST00000401605.5
Gencode Gene: ENSG00000115295.21
Transcript (Including UTRs)
Position: hg38 chr2:29,097,705-29,174,713 Size: 77,009 Total Exon Count: 15 Strand: +
Coding Region
Position: hg38 chr2:29,121,389-29,174,449 Size: 53,061 Coding Exon Count: 14
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CLIP4_HUMAN
DESCRIPTION: RecName: Full=CAP-Gly domain-containing linker protein 4; AltName: Full=Restin-like protein 2;
SIMILARITY: Contains 3 ANK repeats.SIMILARITY: Contains 3 CAP-Gly domains.SEQUENCE CAUTION: Sequence=BAB14974.1; Type=Erroneous initiation;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom
IPR000938 - CAP-Gly_domain
Pfam Domains: PF12796 - Ankyrin repeats (3 copies)
PF01302 - CAP-Gly domain
Protein Data Bank (PDB) 3-D Structure
ModBase Predicted Comparative 3D Structure on Q8N3C7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005515 protein binding
Cellular Component: GO:0043231 intracellular membrane-bounded organelle
Descriptions from all associated GenBank mRNAs
AF433661 - Homo sapiens unknown mRNA.AK302325 - Homo sapiens cDNA FLJ55798 complete cds, highly similar to Restin-like protein 2.AK291595 - Homo sapiens cDNA FLJ75496 complete cds, highly similar to Homo sapiens restin-like 2 (RSNL2), mRNA.AK057267 - Homo sapiens cDNA FLJ32705 fis, clone TESTI2000600, weakly similar to RESTIN.BC013862 - Homo sapiens CAP-GLY domain containing linker protein family, member 4, mRNA (cDNA clone IMAGE:3923805).AL834443 - Homo sapiens mRNA; cDNA DKFZp761O0610 (from clone DKFZp761O0610).AB209042 - Homo sapiens premature mRNA for hypothetical protein FLJ32705 variant.BC126167 - Homo sapiens CAP-GLY domain containing linker protein family, member 4, mRNA (cDNA clone MGC:161445 IMAGE:8991883), complete cds.BC136331 - Homo sapiens CAP-GLY domain containing linker protein family, member 4, mRNA (cDNA clone MGC:167941 IMAGE:9020318), complete cds.HQ258339 - Synthetic construct Homo sapiens clone IMAGE:100072648 CAP-GLY domain containing linker protein family, member 4 (CLIP4) (CLIP4) gene, encodes complete protein.KJ899560 - Synthetic construct Homo sapiens clone ccsbBroadEn_08954 CLIP4 gene, encodes complete protein.AK304384 - Homo sapiens cDNA FLJ55608 complete cds, highly similar to Restin-like protein 2.BC107760 - Homo sapiens CAP-GLY domain containing linker protein family, member 4, mRNA (cDNA clone IMAGE:4616730), with apparent retained intron.JD167208 - Sequence 148232 from Patent EP1572962.BC015310 - Homo sapiens CAP-GLY domain containing linker protein family, member 4, mRNA (cDNA clone IMAGE:4431888), partial cds.JD558223 - Sequence 539247 from Patent EP1572962.JD333700 - Sequence 314724 from Patent EP1572962.AK225074 - Homo sapiens mRNA for restin-like 2 variant, clone: CAS01594.AK024722 - Homo sapiens cDNA: FLJ21069 fis, clone CAS01594.CU677253 - Synthetic construct Homo sapiens gateway clone IMAGE:100019661 5' read CLIP4 mRNA.KJ906319 - Synthetic construct Homo sapiens clone ccsbBroadEn_15989 CLIP4 gene, encodes complete protein.JD548769 - Sequence 529793 from Patent EP1572962.JD110362 - Sequence 91386 from Patent EP1572962.JD102543 - Sequence 83567 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A0AV10, B2RMQ3, B7Z7N8, CLIP4_HUMAN, ENST00000401605.1, ENST00000401605.2, ENST00000401605.3, ENST00000401605.4, NM_001287528, Q7Z4U3, Q8N3C7, Q96BR7, Q96MA5, Q9H7C0, RSNL2, uc002rmu.1, uc002rmu.2, uc002rmu.3, uc002rmu.4, uc002rmu.5UCSC ID: ENST00000401605.5RefSeq Accession: NM_001287528
Protein: Q8N3C7
(aka CLIP4_HUMAN)
CCDS: CCDS74502.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.