Human Gene CNTNAP5 (ENST00000431078.1) from GENCODE V44
Description: Homo sapiens contactin associated protein family member 5 (CNTNAP5), transcript variant 1, mRNA. (from RefSeq NM_130773) RefSeq Summary (NM_130773): This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000431078.1 Gencode Gene: ENSG00000155052.15 Transcript (Including UTRs) Position: hg38 chr2:124,025,287-124,915,287 Size: 890,001 Total Exon Count: 24 Strand: + Coding Region Position: hg38 chr2:124,025,651-124,914,288 Size: 888,638 Coding Exon Count: 24
ID:CNTP5_HUMAN DESCRIPTION: RecName: Full=Contactin-associated protein-like 5; AltName: Full=Cell recognition molecule Caspr5; Flags: Precursor; FUNCTION: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential). SIMILARITY: Belongs to the neurexin family. SIMILARITY: Contains 2 EGF-like domains. SIMILARITY: Contains 1 F5/8 type C domain. SIMILARITY: Contains 1 fibrinogen C-terminal domain. SIMILARITY: Contains 4 laminin G-like domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00754 - F5/8 type C domain PF02210 - Laminin G domain
ModBase Predicted Comparative 3D Structure on Q8WYK1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
