Human Gene FAM124B (ENST00000389874.3) from GENCODE V44
Description: Homo sapiens family with sequence similarity 124 member B (FAM124B), transcript variant 2, mRNA. (from RefSeq NM_024785)
Gencode Transcript: ENST00000389874.3
Gencode Gene: ENSG00000124019.10
Transcript (Including UTRs)
Position: hg38 chr2:224,378,698-224,401,994 Size: 23,297 Total Exon Count: 3 Strand: -
Coding Region
Position: hg38 chr2:224,400,419-224,401,768 Size: 1,350 Coding Exon Count: 2
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: F124B_HUMAN
DESCRIPTION: RecName: Full=Protein FAM124B;
INTERACTION: Q99750:MDFI; NbExp=4; IntAct=EBI-741626, EBI-724076;SIMILARITY: Belongs to the FAM124 family.SEQUENCE CAUTION: Sequence=BAB15471.1; Type=Frameshift; Positions=264;
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q9H5Z6
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC025754 - Homo sapiens family with sequence similarity 124B, mRNA (cDNA clone MGC:34161 IMAGE:5202295), complete cds.AK026399 - Homo sapiens cDNA: FLJ22746 fis, clone HUV01174.AK075126 - Homo sapiens cDNA FLJ90645 fis, clone PLACE1004199.JD164605 - Sequence 145629 from Patent EP1572962.JD538726 - Sequence 519750 from Patent EP1572962.JD060327 - Sequence 41351 from Patent EP1572962.JD403583 - Sequence 384607 from Patent EP1572962.JD160271 - Sequence 141295 from Patent EP1572962.JD540459 - Sequence 521483 from Patent EP1572962.JD538914 - Sequence 519938 from Patent EP1572962.JD373743 - Sequence 354767 from Patent EP1572962.JD155578 - Sequence 136602 from Patent EP1572962.JD137224 - Sequence 118248 from Patent EP1572962.JD227330 - Sequence 208354 from Patent EP1572962.JD193477 - Sequence 174501 from Patent EP1572962.JD334368 - Sequence 315392 from Patent EP1572962.JD285339 - Sequence 266363 from Patent EP1572962.JD093394 - Sequence 74418 from Patent EP1572962.JD330388 - Sequence 311412 from Patent EP1572962.JD407966 - Sequence 388990 from Patent EP1572962.JD159389 - Sequence 140413 from Patent EP1572962.JD188289 - Sequence 169313 from Patent EP1572962.JD041247 - Sequence 22271 from Patent EP1572962.JD339779 - Sequence 320803 from Patent EP1572962.JD065520 - Sequence 46544 from Patent EP1572962.JD107854 - Sequence 88878 from Patent EP1572962.JD119237 - Sequence 100261 from Patent EP1572962.JD275505 - Sequence 256529 from Patent EP1572962.JD530798 - Sequence 511822 from Patent EP1572962.HQ447160 - Synthetic construct Homo sapiens clone IMAGE:100070448; CCSB008273_01 family with sequence similarity 124B (FAM124B) gene, encodes complete protein.KJ894742 - Synthetic construct Homo sapiens clone ccsbBroadEn_04136 FAM124B gene, encodes complete protein.CU693050 - Synthetic construct Homo sapiens gateway clone IMAGE:100016944 5' read FAM124B mRNA.JD168844 - Sequence 149868 from Patent EP1572962.JD142786 - Sequence 123810 from Patent EP1572962.JD232909 - Sequence 213933 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A6NNC7, ENST00000389874.1, ENST00000389874.2, F124B_HUMAN, NM_024785, Q8NBZ4, Q8TAV7, Q9H5Z6, uc002vnw.1, uc002vnw.2, uc002vnw.3UCSC ID: ENST00000389874.3RefSeq Accession: NM_024785
Protein: Q9H5Z6
(aka F124B_HUMAN)
CCDS: CCDS2461.1
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.