Description: Homo sapiens TPD52 like 2 (TPD52L2), transcript variant 1, mRNA. (from RefSeq NM_199360) RefSeq Summary (NM_199360): This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]. Gencode Transcript: ENST00000217121.9 Gencode Gene: ENSG00000101150.18 Transcript (Including UTRs) Position: hg38 chr20:63,865,294-63,891,545 Size: 26,252 Total Exon Count: 9 Strand: + Coding Region Position: hg38 chr20:63,865,366-63,889,945 Size: 24,580 Coding Exon Count: 9
ID:TPD54_HUMAN DESCRIPTION: RecName: Full=Tumor protein D54; Short=hD54; AltName: Full=Tumor protein D52-like 2; SUBUNIT: Forms homodimer or heterodimer with other members of the family (By similarity). Interacts with MAL2. INTERACTION: Q62393:Tpd52 (xeno); NbExp=2; IntAct=EBI-782616, EBI-782591; SIMILARITY: Belongs to the TPD52 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O43399
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.