Human Gene GUCD1 (ENST00000407471.7) from GENCODE V44
Description: Homo sapiens guanylyl cyclase domain containing 1 (GUCD1), transcript variant 4, mRNA. (from RefSeq NM_031444)
Gencode Transcript: ENST00000407471.7
Gencode Gene: ENSG00000138867.17
Transcript (Including UTRs)
Position: hg38 chr22:24,540,438-24,555,182 Size: 14,745 Total Exon Count: 6 Strand: -
Coding Region
Position: hg38 chr22:24,543,006-24,554,991 Size: 11,986 Coding Exon Count: 6
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CV013_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C22orf13; AltName: Full=Protein LLN4;
SEQUENCE CAUTION: Sequence=BAB68411.1; Type=Erroneous initiation;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR018616 - Guanylyl_cyclase
Pfam Domains: PF09778 - Guanylylate cyclase
ModBase Predicted Comparative 3D Structure on Q96NT3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC004144 - Homo sapiens chromosome 22 open reading frame 13, mRNA (cDNA clone IMAGE:2819509).AK024723 - Homo sapiens cDNA: FLJ21070 fis, clone CAS01707.BC041568 - Homo sapiens chromosome 22 open reading frame 13, mRNA (cDNA clone IMAGE:3504340), partial cds.AK025242 - Homo sapiens cDNA: FLJ21589 fis, clone COL06960.BC015685 - Homo sapiens chromosome 22 open reading frame 13, mRNA (cDNA clone IMAGE:4650618), partial cds.BC053529 - Homo sapiens chromosome 22 open reading frame 13, mRNA (cDNA clone IMAGE:3848564), partial cds.BC070109 - Homo sapiens chromosome 22 open reading frame 13, mRNA (cDNA clone MGC:87632 IMAGE:4838028), complete cds.BC002924 - Homo sapiens chromosome 22 open reading frame 13, mRNA (cDNA clone IMAGE:3956179), partial cds.AK054681 - Homo sapiens cDNA FLJ30119 fis, clone BRACE1000070.JD426081 - Sequence 407105 from Patent EP1572962.JD338732 - Sequence 319756 from Patent EP1572962.JD371821 - Sequence 352845 from Patent EP1572962.JD377377 - Sequence 358401 from Patent EP1572962.JD087384 - Sequence 68408 from Patent EP1572962.JD324620 - Sequence 305644 from Patent EP1572962.JD355764 - Sequence 336788 from Patent EP1572962.JD099447 - Sequence 80471 from Patent EP1572962.JD434372 - Sequence 415396 from Patent EP1572962.JD550538 - Sequence 531562 from Patent EP1572962.JD488749 - Sequence 469773 from Patent EP1572962.JD278464 - Sequence 259488 from Patent EP1572962.JD449048 - Sequence 430072 from Patent EP1572962.KJ903352 - Synthetic construct Homo sapiens clone ccsbBroadEn_12746 C22orf13 gene, encodes complete protein.JD155966 - Sequence 136990 from Patent EP1572962.JD081004 - Sequence 62028 from Patent EP1572962.JD493125 - Sequence 474149 from Patent EP1572962.JD041621 - Sequence 22645 from Patent EP1572962.JD169510 - Sequence 150534 from Patent EP1572962.JD342204 - Sequence 323228 from Patent EP1572962.JD522073 - Sequence 503097 from Patent EP1572962.JD275970 - Sequence 256994 from Patent EP1572962.JD466759 - Sequence 447783 from Patent EP1572962.JD242676 - Sequence 223700 from Patent EP1572962.JD262186 - Sequence 243210 from Patent EP1572962.JD441655 - Sequence 422679 from Patent EP1572962.JD266103 - Sequence 247127 from Patent EP1572962.JD300610 - Sequence 281634 from Patent EP1572962.JD266102 - Sequence 247126 from Patent EP1572962.JD271487 - Sequence 252511 from Patent EP1572962.JD474892 - Sequence 455916 from Patent EP1572962.JD562905 - Sequence 543929 from Patent EP1572962.JD475464 - Sequence 456488 from Patent EP1572962.JD224838 - Sequence 205862 from Patent EP1572962.JD270475 - Sequence 251499 from Patent EP1572962.JD066188 - Sequence 47212 from Patent EP1572962.JD382868 - Sequence 363892 from Patent EP1572962.JD474786 - Sequence 455810 from Patent EP1572962.JD466548 - Sequence 447572 from Patent EP1572962.JD067182 - Sequence 48206 from Patent EP1572962.JD479896 - Sequence 460920 from Patent EP1572962.JD263863 - Sequence 244887 from Patent EP1572962.JD469392 - Sequence 450416 from Patent EP1572962.JD068914 - Sequence 49938 from Patent EP1572962.JD317487 - Sequence 298511 from Patent EP1572962.JD335726 - Sequence 316750 from Patent EP1572962.JD115014 - Sequence 96038 from Patent EP1572962.JD190895 - Sequence 171919 from Patent EP1572962.JD051151 - Sequence 32175 from Patent EP1572962.JD051150 - Sequence 32174 from Patent EP1572962.AK098754 - Homo sapiens cDNA FLJ25888 fis, clone CBR03058.JD355990 - Sequence 337014 from Patent EP1572962.JD267846 - Sequence 248870 from Patent EP1572962.JD489797 - Sequence 470821 from Patent EP1572962.JD270864 - Sequence 251888 from Patent EP1572962.JD231194 - Sequence 212218 from Patent EP1572962.JD339158 - Sequence 320182 from Patent EP1572962.JD199380 - Sequence 180404 from Patent EP1572962.JD253268 - Sequence 234292 from Patent EP1572962.JD384255 - Sequence 365279 from Patent EP1572962.JD295806 - Sequence 276830 from Patent EP1572962.JD372809 - Sequence 353833 from Patent EP1572962.JD546005 - Sequence 527029 from Patent EP1572962.JD190144 - Sequence 171168 from Patent EP1572962.JD200512 - Sequence 181536 from Patent EP1572962.AK296893 - Homo sapiens cDNA FLJ55093 complete cds.JD452085 - Sequence 433109 from Patent EP1572962.JD513688 - Sequence 494712 from Patent EP1572962.AK294972 - Homo sapiens cDNA FLJ61115 complete cds.JD465695 - Sequence 446719 from Patent EP1572962.JD180586 - Sequence 161610 from Patent EP1572962.JD539222 - Sequence 520246 from Patent EP1572962.JD393190 - Sequence 374214 from Patent EP1572962.JD254508 - Sequence 235532 from Patent EP1572962.CU687038 - Synthetic construct Homo sapiens gateway clone IMAGE:100022770 5' read C22orf13 mRNA.HQ447432 - Synthetic construct Homo sapiens clone IMAGE:100070759; CCSB014410_01 chromosome 22 open reading frame 13 (C22orf13) gene, encodes complete protein.KJ903353 - Synthetic construct Homo sapiens clone ccsbBroadEn_12747 C22orf13 gene, encodes complete protein.JD439193 - Sequence 420217 from Patent EP1572962.JD442307 - Sequence 423331 from Patent EP1572962.JD541621 - Sequence 522645 from Patent EP1572962.JD060631 - Sequence 41655 from Patent EP1572962.DQ600107 - Homo sapiens piRNA piR-38173, complete sequence.JD204318 - Sequence 185342 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: B5MCB8, C22orf13, CV013_HUMAN, ENST00000407471.1, ENST00000407471.2, ENST00000407471.3, ENST00000407471.4, ENST00000407471.5, ENST00000407471.6, LLN4, NM_031444, Q96NT3, Q96Q79, Q9BU32, uc003aah.1, uc003aah.2, uc003aah.3, uc003aah.4UCSC ID: ENST00000407471.7RefSeq Accession: NM_031444
Protein: Q96NT3
(aka CV013_HUMAN)
CCDS: CCDS33621.1 , CCDS63426.1
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.