ID:PCNP_HUMAN DESCRIPTION: RecName: Full=PEST proteolytic signal-containing nuclear protein; Short=PCNP; Short=PEST-containing nuclear protein; FUNCTION: May be involved in cell cycle regulation. SUBUNIT: Interacts with UHRF2/NIRF. SUBCELLULAR LOCATION: Nucleus. PTM: Ubiquitinated; mediated by UHRF2 and leading to its subsequent proteasomal degradation.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q8WW12
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007049 cell cycle GO:0016567 protein ubiquitination GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
US Server
