Human Gene CD200 (ENST00000315711.12) from GENCODE V44
Description: Homo sapiens CD200 molecule (CD200), transcript variant 1, mRNA. (from RefSeq NM_005944) RefSeq Summary (NM_005944): This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]. Gencode Transcript: ENST00000315711.12 Gencode Gene: ENSG00000091972.18 Transcript (Including UTRs) Position: hg38 chr3:112,333,156-112,362,812 Size: 29,657 Total Exon Count: 6 Strand: + Coding Region Position: hg38 chr3:112,333,213-112,361,550 Size: 28,338 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P41217
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
