Human Gene RABL3 (ENST00000273375.7) Description and Page Index
  Description: Homo sapiens RAB, member of RAS oncogene family like 3 (RABL3), transcript variant 2, mRNA. (from RefSeq NM_173825)
Gencode Transcript: ENST00000273375.7
Gencode Gene: ENSG00000144840.9
Transcript (Including UTRs)
   Position: hg38 chr3:120,686,681-120,742,537 Size: 55,857 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg38 chr3:120,689,823-120,742,507 Size: 52,685 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:120,686,681-120,742,537)mRNA (may differ from genome)Protein (236 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
HPRDLynxMGIneXtProtOMIMPubMed
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: RABL3_HUMAN
DESCRIPTION: RecName: Full=Rab-like protein 3;
SIMILARITY: Belongs to the small GTPase superfamily. Rab family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.52 RPKM in Adrenal Gland
Total median expression: 281.52 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -2.5030-0.083 Picture PostScript Text
3' UTR -777.403142-0.247 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001806 - Small_GTPase

Pfam Domains:
PF00071 - Ras family

ModBase Predicted Comparative 3D Structure on Q5HYI8
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsemblEnsembl  
Protein SequenceProtein Sequence Protein Sequence  
AlignmentAlignment Alignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000166 nucleotide binding
GO:0005525 GTP binding


-  Descriptions from all associated GenBank mRNAs
  BX647664 - Homo sapiens mRNA; cDNA DKFZp313O171 (from clone DKFZp313O171).
BX647593 - Homo sapiens mRNA; cDNA DKFZp313M1333 (from clone DKFZp313M1333).
BX647559 - Homo sapiens mRNA; cDNA DKFZp313A1611 (from clone DKFZp313A1611).
BC020832 - Homo sapiens RAB, member of RAS oncogene family-like 3, mRNA (cDNA clone MGC:23920 IMAGE:4771781), complete cds.
LF210606 - JP 2014500723-A/18109: Polycomb-Associated Non-Coding RNAs.
MA446183 - JP 2018138019-A/18109: Polycomb-Associated Non-Coding RNAs.
LF213804 - JP 2014500723-A/21307: Polycomb-Associated Non-Coding RNAs.
MA449381 - JP 2018138019-A/21307: Polycomb-Associated Non-Coding RNAs.
AK293085 - Homo sapiens cDNA FLJ75867 complete cds, highly similar to Homo sapiens RAB, member of RAS oncogene family-like 3 (RABL3),mRNA.
KJ900581 - Synthetic construct Homo sapiens clone ccsbBroadEn_09975 RABL3 gene, encodes complete protein.
AB464115 - Synthetic construct DNA, clone: pF1KB7502, Homo sapiens RABL3 gene for RAB, member of RAS oncogene family-like 3, without stop codon, in Flexi system.
AK025772 - Homo sapiens cDNA: FLJ22119 fis, clone HEP18852.
JD096477 - Sequence 77501 from Patent EP1572962.
JD112244 - Sequence 93268 from Patent EP1572962.
JD144560 - Sequence 125584 from Patent EP1572962.
JD283289 - Sequence 264313 from Patent EP1572962.
JD144559 - Sequence 125583 from Patent EP1572962.
JD144561 - Sequence 125585 from Patent EP1572962.
JD212472 - Sequence 193496 from Patent EP1572962.
JD542600 - Sequence 523624 from Patent EP1572962.
JD376010 - Sequence 357034 from Patent EP1572962.
JD497684 - Sequence 478708 from Patent EP1572962.
JD497685 - Sequence 478709 from Patent EP1572962.
JD259497 - Sequence 240521 from Patent EP1572962.
JD122406 - Sequence 103430 from Patent EP1572962.
JD467693 - Sequence 448717 from Patent EP1572962.
JD245122 - Sequence 226146 from Patent EP1572962.
JD453952 - Sequence 434976 from Patent EP1572962.
JD134581 - Sequence 115605 from Patent EP1572962.
LF339233 - JP 2014500723-A/146736: Polycomb-Associated Non-Coding RNAs.
MA574810 - JP 2018138019-A/146736: Polycomb-Associated Non-Coding RNAs.
JD538761 - Sequence 519785 from Patent EP1572962.
JD413690 - Sequence 394714 from Patent EP1572962.
LF339232 - JP 2014500723-A/146735: Polycomb-Associated Non-Coding RNAs.
MA574809 - JP 2018138019-A/146735: Polycomb-Associated Non-Coding RNAs.
JD268765 - Sequence 249789 from Patent EP1572962.
JD394327 - Sequence 375351 from Patent EP1572962.
JD095192 - Sequence 76216 from Patent EP1572962.
JD237733 - Sequence 218757 from Patent EP1572962.
JD241072 - Sequence 222096 from Patent EP1572962.
JD304651 - Sequence 285675 from Patent EP1572962.
JD226774 - Sequence 207798 from Patent EP1572962.
JD549189 - Sequence 530213 from Patent EP1572962.
JD275346 - Sequence 256370 from Patent EP1572962.
LF339231 - JP 2014500723-A/146734: Polycomb-Associated Non-Coding RNAs.
MA574808 - JP 2018138019-A/146734: Polycomb-Associated Non-Coding RNAs.
JD027103 - Sequence 8127 from Patent EP1572962.
JD028578 - Sequence 9602 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_173825, Q5HYI8, Q8WUD3, RABL3_HUMAN, uc003edx.1, uc003edx.2, uc003edx.3
UCSC ID: uc003edx.3
RefSeq Accession: NM_173825
Protein: Q5HYI8 (aka RABL3_HUMAN)
CCDS: CCDS3001.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.