Human Gene RUVBL1 (ENST00000464873.5) from GENCODE V44
Description: Homo sapiens RuvB like AAA ATPase 1 (RUVBL1), transcript variant 3, mRNA. (from RefSeq NM_001319086) RefSeq Summary (NM_001319086): This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]. Gencode Transcript: ENST00000464873.5 Gencode Gene: ENSG00000175792.12 Transcript (Including UTRs) Position: hg38 chr3:128,064,785-128,153,914 Size: 89,130 Total Exon Count: 10 Strand: - Coding Region Position: hg38 chr3:128,065,212-128,119,375 Size: 54,164 Coding Exon Count: 9
ID:E7ETR0_HUMAN DESCRIPTION: SubName: Full=RuvB-like 1; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E7ETR0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006281 DNA repair GO:0006310 DNA recombination GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006974 cellular response to DNA damage stimulus GO:0032508 DNA duplex unwinding