Human Gene WDR49 (ENST00000476376.5) from GENCODE V44
  Description: WD repeat domain 49 (from HGNC WDR49)
RefSeq Summary (NM_001366158): This gene encodes a member of the WD repeat protein family with nine WD repeats. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
Gencode Transcript: ENST00000476376.5
Gencode Gene: ENSG00000174776.12
Transcript (Including UTRs)
   Position: hg38 chr3:167,478,687-167,575,231 Size: 96,545 Total Exon Count: 13 Strand: -


Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:167,478,687-167,575,231)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
EnsemblExonPrimerGencodeHGNCLynxPubMed

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.06 RPKM in Brain - Hypothalamus
Total median expression: 9.51 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC035512 - Homo sapiens WD repeat domain 49, mRNA (cDNA clone MGC:34766 IMAGE:5199615), complete cds.
AK090939 - Homo sapiens cDNA FLJ33620 fis, clone BRAMY2020634.
AX746694 - Sequence 219 from Patent EP1308459.
AK294387 - Homo sapiens cDNA FLJ60484 complete cds, highly similar to Homo sapiens WD repeat domain 49 (WDR49), mRNA.
AK097556 - Homo sapiens cDNA FLJ40237 fis, clone TESTI2023414.
JF432224 - Synthetic construct Homo sapiens clone IMAGE:100073388 WD repeat domain 49 (WDR49) gene, encodes complete protein.
KJ895663 - Synthetic construct Homo sapiens clone ccsbBroadEn_05057 WDR49 gene, encodes complete protein.
JD433695 - Sequence 414719 from Patent EP1572962.
JD495109 - Sequence 476133 from Patent EP1572962.
CU690094 - Synthetic construct Homo sapiens gateway clone IMAGE:100020024 5' read WDR49 mRNA.

-  Other Names for This Gene
  Alternate Gene Symbols: AK090939, ENST00000476376.1, ENST00000476376.2, ENST00000476376.3, ENST00000476376.4, uc003feu.1, uc003feu.2, uc003feu.3
UCSC ID: ENST00000476376.5
RefSeq Accession: NM_001366158

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.