Human Gene WDR49 (ENST00000476376.5) from GENCODE V44
Description: WD repeat domain 49 (from HGNC WDR49) RefSeq Summary (NM_001366158): This gene encodes a member of the WD repeat protein family with nine WD repeats. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Gencode Transcript: ENST00000476376.5 Gencode Gene: ENSG00000174776.12 Transcript (Including UTRs) Position: hg38 chr3:167,478,687-167,575,231 Size: 96,545 Total Exon Count: 13 Strand: -
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
BC035512 - Homo sapiens WD repeat domain 49, mRNA (cDNA clone MGC:34766 IMAGE:5199615), complete cds. AK090939 - Homo sapiens cDNA FLJ33620 fis, clone BRAMY2020634. AX746694 - Sequence 219 from Patent EP1308459. AK294387 - Homo sapiens cDNA FLJ60484 complete cds, highly similar to Homo sapiens WD repeat domain 49 (WDR49), mRNA. AK097556 - Homo sapiens cDNA FLJ40237 fis, clone TESTI2023414. JF432224 - Synthetic construct Homo sapiens clone IMAGE:100073388 WD repeat domain 49 (WDR49) gene, encodes complete protein. KJ895663 - Synthetic construct Homo sapiens clone ccsbBroadEn_05057 WDR49 gene, encodes complete protein. JD433695 - Sequence 414719 from Patent EP1572962. JD495109 - Sequence 476133 from Patent EP1572962. CU690094 - Synthetic construct Homo sapiens gateway clone IMAGE:100020024 5' read WDR49 mRNA.