Human Gene KIAA0232 (ENST00000425103.5) from GENCODE V44
  Description: Homo sapiens KIAA0232 (KIAA0232), transcript variant 2, mRNA. (from RefSeq NM_001100590)
Gencode Transcript: ENST00000425103.5
Gencode Gene: ENSG00000170871.12
Transcript (Including UTRs)
   Position: hg38 chr4:6,782,732-6,884,170 Size: 101,439 Total Exon Count: 9 Strand: +
Coding Region
   Position: hg38 chr4:6,824,454-6,880,966 Size: 56,513 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:6,782,732-6,884,170)mRNA (may differ from genome)Protein (1395 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCLynxMGIneXtProtPubMedUniProtKB
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: K0232_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein KIAA0232;
SEQUENCE CAUTION: Sequence=BAA13221.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
  • D019327 Copper Sulfate

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 14.12 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 424.87 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -125.80379-0.332 Picture PostScript Text
3' UTR -927.603204-0.290 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q92628
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl   
Protein SequenceProtein SequenceProtein Sequence   
AlignmentAlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0000166 nucleotide binding
GO:0005524 ATP binding


-  Descriptions from all associated GenBank mRNAs
  D86985 - Homo sapiens KIAA0232 mRNA for KIAA0232 protein.
BC150286 - Homo sapiens KIAA0232, mRNA (cDNA clone MGC:166909 IMAGE:8860111), complete cds.
AK124715 - Homo sapiens cDNA FLJ42725 fis, clone BRAWH2001424.
EF553521 - Homo sapiens clone DKFZp686E178 KIAA0232 (KIAA0232) mRNA, complete cds.
JD404739 - Sequence 385763 from Patent EP1572962.
JD464966 - Sequence 445990 from Patent EP1572962.
JD389872 - Sequence 370896 from Patent EP1572962.
JD129059 - Sequence 110083 from Patent EP1572962.
JD378866 - Sequence 359890 from Patent EP1572962.
JD377923 - Sequence 358947 from Patent EP1572962.
JD511763 - Sequence 492787 from Patent EP1572962.
JD541194 - Sequence 522218 from Patent EP1572962.
JD039870 - Sequence 20894 from Patent EP1572962.
AB385298 - Synthetic construct DNA, clone: pF1KA0232, Homo sapiens KIAA0232 gene for KIAA0232 protein, complete cds, without stop codon, in Flexi system.
KJ898089 - Synthetic construct Homo sapiens clone ccsbBroadEn_07483 KIAA0232 gene, encodes complete protein.
JD501241 - Sequence 482265 from Patent EP1572962.
JD093177 - Sequence 74201 from Patent EP1572962.
JD089167 - Sequence 70191 from Patent EP1572962.
JD433581 - Sequence 414605 from Patent EP1572962.
JD454194 - Sequence 435218 from Patent EP1572962.
JD213818 - Sequence 194842 from Patent EP1572962.
JD170402 - Sequence 151426 from Patent EP1572962.
JD196156 - Sequence 177180 from Patent EP1572962.
JD353867 - Sequence 334891 from Patent EP1572962.
JD048395 - Sequence 29419 from Patent EP1572962.
JD314489 - Sequence 295513 from Patent EP1572962.
JD520459 - Sequence 501483 from Patent EP1572962.
JD281916 - Sequence 262940 from Patent EP1572962.
JD115096 - Sequence 96120 from Patent EP1572962.
JD179460 - Sequence 160484 from Patent EP1572962.
JD338856 - Sequence 319880 from Patent EP1572962.
JD198922 - Sequence 179946 from Patent EP1572962.
JD487815 - Sequence 468839 from Patent EP1572962.
JD139407 - Sequence 120431 from Patent EP1572962.
JD414016 - Sequence 395040 from Patent EP1572962.
JD495184 - Sequence 476208 from Patent EP1572962.
JD094758 - Sequence 75782 from Patent EP1572962.
JD064414 - Sequence 45438 from Patent EP1572962.
JD510769 - Sequence 491793 from Patent EP1572962.
JD419761 - Sequence 400785 from Patent EP1572962.
JD530541 - Sequence 511565 from Patent EP1572962.
JD224397 - Sequence 205421 from Patent EP1572962.
JD248792 - Sequence 229816 from Patent EP1572962.
JD303694 - Sequence 284718 from Patent EP1572962.
JD113994 - Sequence 95018 from Patent EP1572962.
AF143884 - Homo sapiens clone IMAGE:121558 mRNA sequence.
JD047235 - Sequence 28259 from Patent EP1572962.
JD336781 - Sequence 317805 from Patent EP1572962.
CR457160 - Homo sapiens full open reading frame cDNA clone RZPDo834B058D for gene KIAA0232, KIAA0232 gene product; complete cds, incl. stopcodon.
JD376587 - Sequence 357611 from Patent EP1572962.
JD549329 - Sequence 530353 from Patent EP1572962.
JD503492 - Sequence 484516 from Patent EP1572962.
JD166797 - Sequence 147821 from Patent EP1572962.
JD509467 - Sequence 490491 from Patent EP1572962.
JD248453 - Sequence 229477 from Patent EP1572962.
JD299137 - Sequence 280161 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A7E2D2, ENST00000425103.1, ENST00000425103.2, ENST00000425103.3, ENST00000425103.4, K0232_HUMAN, NM_001100590, Q92628, uc003gjq.1, uc003gjq.2, uc003gjq.3, uc003gjq.4, uc003gjq.5
UCSC ID: ENST00000425103.5
RefSeq Accession: NM_001100590
Protein: Q92628 (aka K0232_HUMAN)
CCDS: CCDS43209.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.