Human Gene FGFBP2 (ENST00000259989.7) from GENCODE V44
Description: Homo sapiens fibroblast growth factor binding protein 2 (FGFBP2), mRNA. (from RefSeq NM_031950) RefSeq Summary (NM_031950): This gene encodes a member of the fibroblast growth factor binding protein family. The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte-mediated immunity. An increase in the amount of gene product may be associated with atopic asthma and mild extrinsic asthma.[provided by RefSeq Staff, Oct 2008]. Gencode Transcript: ENST00000259989.7 Gencode Gene: ENSG00000137441.8 Transcript (Including UTRs) Position: hg38 chr4:15,960,245-15,963,175 Size: 2,931 Total Exon Count: 2 Strand: - Coding Region Position: hg38 chr4:15,962,458-15,963,129 Size: 672 Coding Exon Count: 1
ID:FGFP2_HUMAN DESCRIPTION: RecName: Full=Fibroblast growth factor-binding protein 2; Short=FGF-BP2; Short=FGF-binding protein 2; Short=FGFBP-2; AltName: Full=37 kDa killer-specific secretory protein; Short=Ksp37; AltName: Full=HBp17-related protein; Short=HBp17-RP; Flags: Precursor; SUBCELLULAR LOCATION: Secreted, extracellular space. TISSUE SPECIFICITY: Expressed in serum, peripheral leukocytes and cytotoxic T-lymphocytes, but not in granulocytes and monocytes (at protein level). SIMILARITY: Belongs to the fibroblast growth factor-binding protein family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF06473 - FGF binding protein 1 (FGF-BP1)
ModBase Predicted Comparative 3D Structure on Q9BYJ0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
