Human Gene TMED7-TICAM2 (ENST00000282382.8) from GENCODE V44
Description: Homo sapiens TMED7-TICAM2 readthrough (TMED7-TICAM2), transcript variant 1, mRNA. (from RefSeq NM_001164468) RefSeq Summary (NM_001164469): This locus represents naturally occurring read-through transcription between the neighboring transmembrane emp24 protein transport domain containing 7 (TMED7) and toll-like receptor adaptor molecule 2 (TICAM2) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. This fusion product functions to negatively regulate the adaptor MyD88-independent toll-like receptor 4 pathway. [provided by RefSeq, Nov 2010]. Gencode Transcript: ENST00000282382.8 Gencode Gene: ENSG00000251201.8 Transcript (Including UTRs) Position: hg38 chr5:115,578,642-115,626,161 Size: 47,520 Total Exon Count: 4 Strand: - Coding Region Position: hg38 chr5:115,580,549-115,625,792 Size: 45,244 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
