Human Gene TRIM10 (ENST00000449742.7) Description and Page Index
Description: Homo sapiens tripartite motif containing 10 (TRIM10), transcript variant 1, mRNA. (from RefSeq NM_006778) RefSeq Summary (NM_006778): The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000449742.7 Gencode Gene: ENSG00000204613.11 Transcript (Including UTRs) Position: hg38 chr6:30,151,943-30,161,211 Size: 9,269 Total Exon Count: 7 Strand: - Coding Region Position: hg38 chr6:30,153,969-30,160,858 Size: 6,890 Coding Exon Count: 7
ID:TRI10_HUMAN DESCRIPTION: RecName: Full=Tripartite motif-containing protein 10; AltName: Full=B30-RING finger protein; AltName: Full=RING finger protein 9; FUNCTION: Seems to play an important role in erythropoiesis (By similarity). SUBCELLULAR LOCATION: Cytoplasm. SIMILARITY: Belongs to the TRIM/RBCC family. SIMILARITY: Contains 1 B box-type zinc finger. SIMILARITY: Contains 1 B30.2/SPRY domain. SIMILARITY: Contains 1 RING-type zinc finger.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UDY6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.