ID:OOEP_HUMAN DESCRIPTION: RecName: Full=Oocyte-expressed protein homolog; AltName: Full=KH homology domain-containing protein 2; AltName: Full=Oocyte- and embryo-specific protein 19; Short=hOEP19; FUNCTION: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions (By similarity). SUBUNIT: Component of the SCMC which also includes at least NLRP5 and TLE6 (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). DOMAIN: Contains an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA. SIMILARITY: Belongs to the KHDC1 family. SIMILARITY: Contains 1 KH domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on A6NGQ2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.