Human Gene TRIM4 (ENST00000349062.6) Description and Page Index
Description: Homo sapiens tripartite motif containing 4 (TRIM4), transcript variant beta, mRNA. (from RefSeq NM_033091) RefSeq Summary (NM_033091): The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010]. Gencode Transcript: ENST00000349062.6 Gencode Gene: ENSG00000146833.15 Transcript (Including UTRs) Position: hg38 chr7:99,890,413-99,919,600 Size: 29,188 Total Exon Count: 6 Strand: - Coding Region Position: hg38 chr7:99,892,163-99,919,401 Size: 27,239 Coding Exon Count: 6
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9C037
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary