Human Gene NAT16 (ENST00000300303.7) from GENCODE V44
  Description: Homo sapiens N-acetyltransferase 16 (putative) (NAT16), transcript variant 1, mRNA. (from RefSeq NM_198571)
Gencode Transcript: ENST00000300303.7
Gencode Gene: ENSG00000167011.9
Transcript (Including UTRs)
   Position: hg38 chr7:101,170,496-101,180,293 Size: 9,798 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg38 chr7:101,172,079-101,174,807 Size: 2,729 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:101,170,496-101,180,293)mRNA (may differ from genome)Protein (369 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGencodeGeneCards
HGNCHPRDLynxMalacardsMGIneXtProt
OMIMPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: NAT16_HUMAN
DESCRIPTION: RecName: Full=Putative N-acetyltransferase 16; EC=2.3.1.-;
SIMILARITY: Contains 1 N-acetyltransferase domain.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 2.45 RPKM in Pituitary
Total median expression: 9.15 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -123.80256-0.484 Picture PostScript Text
3' UTR -552.401583-0.349 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR016181 - Acyl_CoA_acyltransferase
IPR000182 - GNAT_dom

ModBase Predicted Comparative 3D Structure on Q8N8M0
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups

Biological Process:
GO:0006473 protein acetylation


-  Descriptions from all associated GenBank mRNAs
  AL831911 - Homo sapiens mRNA; cDNA DKFZp547K159 (from clone DKFZp547K159).
AK092119 - Homo sapiens cDNA FLJ34800 fis, clone NT2NE2006288.
AX747364 - Sequence 889 from Patent EP1308459.
AK096556 - Homo sapiens cDNA FLJ39237 fis, clone OCBBF2007931.
BC104841 - Homo sapiens chromosome 7 open reading frame 52, mRNA (cDNA clone MGC:132501 IMAGE:8143844), complete cds.
KJ900678 - Synthetic construct Homo sapiens clone ccsbBroadEn_10072 NAT16 gene, encodes complete protein.
BC037583 - Homo sapiens, clone IMAGE:5242255, mRNA.
JD475636 - Sequence 456660 from Patent EP1572962.
JD499252 - Sequence 480276 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C7orf52, ENST00000300303.1, ENST00000300303.2, ENST00000300303.3, ENST00000300303.4, ENST00000300303.5, ENST00000300303.6, NAT16_HUMAN, NM_198571, Q8N8M0, Q8NDR1, uc003uxy.1, uc003uxy.2, uc003uxy.3
UCSC ID: ENST00000300303.7
RefSeq Accession: NM_198571
Protein: Q8N8M0 (aka NAT16_HUMAN)
CCDS: CCDS5713.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.