Human Gene CNOT4 (ENST00000361528.8) from GENCODE V44
Description: Homo sapiens CCR4-NOT transcription complex subunit 4 (CNOT4), transcript variant 1, mRNA. (from RefSeq NM_013316) RefSeq Summary (NM_013316): The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]. Gencode Transcript: ENST00000361528.8 Gencode Gene: ENSG00000080802.21 Transcript (Including UTRs) Position: hg38 chr7:135,362,885-135,510,091 Size: 147,207 Total Exon Count: 11 Strand: - Coding Region Position: hg38 chr7:135,362,885-135,438,331 Size: 75,447 Coding Exon Count: 10
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O95628
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.