Human Gene CA2 (ENST00000285379.10) from GENCODE V44
Description: Homo sapiens carbonic anhydrase 2 (CA2), transcript variant 2, mRNA. (from RefSeq NM_001293675) RefSeq Summary (NM_000067): The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]. Gencode Transcript: ENST00000285379.10 Gencode Gene: ENSG00000104267.10 Transcript (Including UTRs) Position: hg38 chr8:85,464,007-85,481,493 Size: 17,487 Total Exon Count: 7 Strand: + Coding Region Position: hg38 chr8:85,464,082-85,480,789 Size: 16,708 Coding Exon Count: 7
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.