Human Gene MATN2 (ENST00000254898.7) from GENCODE V44
Description: Homo sapiens matrilin 2 (MATN2), transcript variant 1, mRNA. (from RefSeq NM_002380) RefSeq Summary (NM_002380): This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000254898.7 Gencode Gene: ENSG00000132561.14 Transcript (Including UTRs) Position: hg38 chr8:97,869,064-98,036,724 Size: 167,661 Total Exon Count: 19 Strand: + Coding Region Position: hg38 chr8:97,888,101-98,035,712 Size: 147,612 Coding Exon Count: 18
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00008 - EGF-like domain PF07645 - Calcium-binding EGF domain PF10393 - Trimeric coiled-coil oligomerisation domain of matrilin PF00092 - von Willebrand factor type A domain
ModBase Predicted Comparative 3D Structure on O00339
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
