Human Gene EIF3H (ENST00000521861.6) from GENCODE V44
Description: Homo sapiens eukaryotic translation initiation factor 3 subunit H (EIF3H), mRNA. (from RefSeq NM_003756)
Gencode Transcript: ENST00000521861.6
Gencode Gene: ENSG00000147677.12
Transcript (Including UTRs)
Position: hg38 chr8:116,642,130-116,755,823 Size: 113,694 Total Exon Count: 8 Strand: -
Coding Region
Position: hg38 chr8:116,645,006-116,755,797 Size: 110,792 Coding Exon Count: 8
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000555 - JAB1_Mov34_MPN_PAD1
Pfam Domains: PF01398 - JAB1/Mov34/MPN/PAD-1 ubiquitin protease
ModBase Predicted Comparative 3D Structure on Q6IB98
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0003743 translation initiation factor activity
GO:0005515 protein binding
Biological Process: GO:0001732 formation of cytoplasmic translation initiation complex
GO:0002183 cytoplasmic translational initiation
GO:0006412 translation
GO:0006413 translational initiation
Cellular Component: GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
Descriptions from all associated GenBank mRNAs
BC000386 - Homo sapiens eukaryotic translation initiation factor 3, subunit H, mRNA (cDNA clone MGC:8431 IMAGE:2821133), complete cds.BC090880 - Homo sapiens eukaryotic translation initiation factor 3, subunit H, mRNA (cDNA clone MGC:102958 IMAGE:30367209), complete cds.AK222520 - Homo sapiens mRNA for eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa variant, clone: adSE01270.AK093128 - Homo sapiens cDNA FLJ35809 fis, clone TESTI2006016, highly similar to Eukaryotic translation initiation factor 3 subunit 3.U54559 - Homo sapiens translation initiation factor eIF3 p40 subunit mRNA, complete cds.AK222620 - Homo sapiens mRNA for eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa variant, clone: CBL00213.CR456906 - Homo sapiens full open reading frame cDNA clone RZPDo834F0211D for gene EIF3S3, eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa; complete cds, incl. stopcodon.BT019594 - Homo sapiens eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa mRNA, complete cds.KJ892591 - Synthetic construct Homo sapiens clone ccsbBroadEn_01985 EIF3H gene, encodes complete protein.CU674186 - Synthetic construct Homo sapiens gateway clone IMAGE:100018172 5' read EIF3H mRNA.JD352599 - Sequence 333623 from Patent EP1572962.AK296162 - Homo sapiens cDNA FLJ57508 complete cds, highly similar to Eukaryotic translation initiation factor 3 subunit 3.
Other Names for This Gene
Alternate Gene Symbols: EIF3S3, ENST00000521861.1, ENST00000521861.2, ENST00000521861.3, ENST00000521861.4, ENST00000521861.5, hCG_20900, NM_003756, Q6IB98, Q6IB98_HUMAN, uc003yoa.1, uc003yoa.2, uc003yoa.3, uc003yoa.4, uc003yoa.5UCSC ID: ENST00000521861.6RefSeq Accession: NM_003756
Protein: Q6IB98
CCDS: CCDS6319.1
Methods, Credits, and Use Restrictions
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