Human Gene PTRH1 (ENST00000543175.5) from GENCODE V44
Description: Homo sapiens peptidyl-tRNA hydrolase 1 homolog (PTRH1), transcript variant 1, mRNA. (from RefSeq NM_001002913)
Gencode Transcript: ENST00000543175.5
Gencode Gene: ENSG00000187024.15
Transcript (Including UTRs)
Position: hg38 chr9:127,713,807-127,715,663 Size: 1,857 Total Exon Count: 5 Strand: -
Coding Region
Position: hg38 chr9:127,714,100-127,715,639 Size: 1,540 Coding Exon Count: 5
Data last updated at UCSC: 2023-08-18 00:09:47
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: PTH_HUMAN
DESCRIPTION: RecName: Full=Probable peptidyl-tRNA hydrolase; Short=PTH; EC=3.1.1.29;
CATALYTIC ACTIVITY: N-substituted aminoacyl-tRNA + H(2)O = N- substituted amino acid + tRNA.INTERACTION: P04156:PRNP; NbExp=1; IntAct=EBI-2602515, EBI-977302;SIMILARITY: Belongs to the PTH family.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR001328 - Pept_tRNA_hydro
IPR018171 - Pept_tRNA_hydro_CS
Pfam Domains: PF01195 - Peptidyl-tRNA hydrolase
ModBase Predicted Comparative 3D Structure on Q86Y79
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF205651 - JP 2014500723-A/13154: Polycomb-Associated Non-Coding RNAs.MA441228 - JP 2018138019-A/13154: Polycomb-Associated Non-Coding RNAs.BC032117 - Homo sapiens cDNA clone IMAGE:4908933, partial cds.BC015230 - Homo sapiens peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:3899552), containing frame-shift errors.JD354747 - Sequence 335771 from Patent EP1572962.JD449546 - Sequence 430570 from Patent EP1572962.JD310480 - Sequence 291504 from Patent EP1572962.AK090922 - Homo sapiens cDNA FLJ33603 fis, clone BRAMY2014387, weakly similar to PEPTIDYL-TRNA HYDROLASE (EC 3.1.1.29).AX746684 - Sequence 209 from Patent EP1308459.BC047012 - Homo sapiens peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae), mRNA (cDNA clone MGC:51999 IMAGE:5001221), complete cds.JD525842 - Sequence 506866 from Patent EP1572962.JD116502 - Sequence 97526 from Patent EP1572962.JD098084 - Sequence 79108 from Patent EP1572962.JD270310 - Sequence 251334 from Patent EP1572962.JD346994 - Sequence 328018 from Patent EP1572962.HQ257888 - Synthetic construct Homo sapiens clone IMAGE:100072197 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) (PTRH1) gene, encodes complete protein.KJ895525 - Synthetic construct Homo sapiens clone ccsbBroadEn_04919 PTRH1 gene, encodes complete protein.LF346846 - JP 2014500723-A/154349: Polycomb-Associated Non-Coding RNAs.MA582423 - JP 2018138019-A/154349: Polycomb-Associated Non-Coding RNAs.LF346845 - JP 2014500723-A/154348: Polycomb-Associated Non-Coding RNAs.MA582422 - JP 2018138019-A/154348: Polycomb-Associated Non-Coding RNAs.LF346844 - JP 2014500723-A/154347: Polycomb-Associated Non-Coding RNAs.MA582421 - JP 2018138019-A/154347: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: C9orf115, ENST00000543175.1, ENST00000543175.2, ENST00000543175.3, ENST00000543175.4, NM_001002913, PTH_HUMAN, Q86Y79, uc004bro.1, uc004bro.2, uc004bro.3, uc004bro.4, uc004bro.5UCSC ID: ENST00000543175.5RefSeq Accession: NM_001002913
Protein: Q86Y79
(aka PTH_HUMAN)
CCDS: CCDS35147.1
Methods, Credits, and Use Restrictions
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