Human Gene RABL6 (ENST00000311502.12) from GENCODE V44
Description: Homo sapiens RAB, member RAS oncogene family like 6 (RABL6), transcript variant 1, mRNA. (from RefSeq NM_024718) RefSeq Summary (NM_024718): This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in breast cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. Gencode Transcript: ENST00000311502.12 Gencode Gene: ENSG00000196642.19 Transcript (Including UTRs) Position: hg38 chr9:136,807,948-136,841,187 Size: 33,240 Total Exon Count: 15 Strand: + Coding Region Position: hg38 chr9:136,808,197-136,840,522 Size: 32,326 Coding Exon Count: 15
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF08477 - Ras of Complex, Roc, domain of DAPkinase
ModBase Predicted Comparative 3D Structure on Q3YEC7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.