ID:PRS39_MOUSE DESCRIPTION: RecName: Full=Inactive serine protease 39; AltName: Full=Inactive testicular serine protease 1; Flags: Precursor; FUNCTION: May play an important role in the sperm/egg interaction; released during the acrosome reaction. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted. TISSUE SPECIFICITY: Expressed in testis. More specifically, abundantly expressed in the haploid round spermatid. MISCELLANEOUS: There appears to be no human ortholog of this protein. SIMILARITY: Belongs to the peptidase S1 family. SIMILARITY: Contains 1 peptidase S1 domain. CAUTION: In contrast to other members of the family, lacks the conserved Asp at position 158, which is replaced by an Asn residue, suggesting it is inactive.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O70169
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
