Mouse Gene Poglut2 (ENSMUST00000065767.8) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus protein O-glucosyltransferase 2 (Poglut2), mRNA. (from RefSeq NM_023645)
Gencode Transcript: ENSMUST00000065767.8
Gencode Gene: ENSMUSG00000026047.13
Transcript (Including UTRs)
   Position: mm10 chr1:44,106,546-44,118,808 Size: 12,263 Total Exon Count: 10 Strand: -
Coding Region
   Position: mm10 chr1:44,107,087-44,118,499 Size: 11,413 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:44,106,546-44,118,808)mRNA (may differ from genome)Protein (502 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: KDEL1_MOUSE
DESCRIPTION: RecName: Full=KDEL motif-containing protein 1; AltName: Full=Endoplasmic reticulum resident protein 58; Short=ER protein 58; Short=ERp58; Flags: Precursor;
SUBCELLULAR LOCATION: Endoplasmic reticulum lumen.
TISSUE SPECIFICITY: Widely expressed.
DEVELOPMENTAL STAGE: Expressed in various fetal tissues.
PTM: N-glycosylated.
SIMILARITY: Belongs to the KDELC family.
SIMILARITY: Contains 1 filamin repeat.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -101.70309-0.329 Picture PostScript Text
3' UTR -116.60541-0.216 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001298 - Filamin
IPR017868 - Filamin/ABP280_repeat-like
IPR013783 - Ig-like_fold
IPR014756 - Ig_E-set
IPR006598 - LipoPS_modifying

Pfam Domains:
PF00630 - Filamin/ABP280 repeat
PF05686 - Glycosyl transferase family 90

SCOP Domains:
81296 - E set domains

ModBase Predicted Comparative 3D Structure on Q9JHP7
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0046527 glucosyltransferase activity

Biological Process:
GO:0006664 glycolipid metabolic process

Cellular Component:
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen


-  Descriptions from all associated GenBank mRNAs
  AK035899 - Mus musculus 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630015O14 product:KDEL containing protein 1, full insert sequence.
BC023141 - Mus musculus KDEL (Lys-Asp-Glu-Leu) containing 1, mRNA (cDNA clone MGC:28356 IMAGE:4018698), complete cds.
AK079701 - Mus musculus 0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430018K15 product:KDEL (Lys-Asp-Glu-Leu) containing 1, full insert sequence.
AK007835 - Mus musculus 10 day old male pancreas cDNA, RIKEN full-length enriched library, clone:1810049A15 product:KDEL containing protein 1, full insert sequence.
AK053315 - Mus musculus 0 day neonate eyeball cDNA, RIKEN full-length enriched library, clone:E130009H02 product:KDEL containing protein 1, full insert sequence.
AK170300 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630043J18 product:KDEL (Lys-Asp-Glu-Leu) containing 1, full insert sequence.
AK192289 - Mus musculus cDNA, clone:Y1G0108G24, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK213463 - Mus musculus cDNA, clone:Y2G0128G15, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK217293 - Mus musculus cDNA, clone:Y2G0141F02, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AJ404004 - Mus musculus mRNA for ER protein 58 (EP58 gene).
AK198736 - Mus musculus cDNA, clone:Y1G0129A12, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK035391 - Mus musculus adult male urinary bladder cDNA, RIKEN full-length enriched library, clone:9530028P10 product:KDEL (Lys-Asp-Glu-Leu) containing 1, full insert sequence.
AK200001 - Mus musculus cDNA, clone:Y1G0133A17, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK077468 - Mus musculus 8 days embryo whole body cDNA, RIKEN full-length enriched library, clone:5730416C13 product:KDEL containing protein 1, full insert sequence.
AK200856 - Mus musculus cDNA, clone:Y1G0136D08, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK206036 - Mus musculus cDNA, clone:Y2G0103I24, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK211914 - Mus musculus cDNA, clone:Y2G0123E10, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK216180 - Mus musculus cDNA, clone:Y2G0137H15, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.
AK216649 - Mus musculus cDNA, clone:Y2G0139B02, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065767, based on BLAT search.

-  Other Names for This Gene
  Alternate Gene Symbols: Ep58, KDEL1_MOUSE, Kdelc1, NM_023645, Q8BPU6, Q8C528, Q8R591, Q9D8P1, Q9JHP7, uc007awb.1, uc007awb.2
UCSC ID: uc007awb.2
RefSeq Accession: NM_023645
Protein: Q9JHP7 (aka KDEL1_MOUSE)
CCDS: CCDS14929.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.