Mouse Gene Map2 (ENSMUST00000114017.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus microtubule-associated protein 2 (Map2), transcript variant 1, mRNA. (from RefSeq NM_001039934)
Gencode Transcript: ENSMUST00000114017.7
Gencode Gene: ENSMUSG00000015222.17
Transcript (Including UTRs)
   Position: mm10 chr1:66,175,313-66,442,028 Size: 266,716 Total Exon Count: 15 Strand: +
Coding Region
   Position: mm10 chr1:66,380,512-66,439,007 Size: 58,496 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:66,175,313-66,442,028)mRNA (may differ from genome)Protein (498 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: Q3TLQ0_MOUSE
DESCRIPTION: RecName: Full=Microtubule-associated protein;
SIMILARITY: Contains 4 Tau/MAP repeats.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -146.61463-0.317 Picture PostScript Text
3' UTR -770.603021-0.255 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001084 - Tau/MAP_tubulin-bd_rpt

Pfam Domains:
PF00418 - Tau and MAP protein, tubulin-binding repeat

ModBase Predicted Comparative 3D Structure on Q3TLQ0
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0015631 tubulin binding

Biological Process:
GO:0001578 microtubule bundle formation
GO:0021954 central nervous system neuron development

Cellular Component:
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule


-  Descriptions from all associated GenBank mRNAs
  AK166380 - Mus musculus mammary gland RCB-0527 Jyg-MC(B) cDNA, RIKEN full-length enriched library, clone:G930004O09 product:microtubule-associated protein 2, full insert sequence.
BC052446 - Mus musculus microtubule-associated protein 2, mRNA (cDNA clone IMAGE:6412797), complete cds.
BC150945 - Mus musculus microtubule-associated protein 2, mRNA (cDNA clone MGC:183856 IMAGE:9087856), complete cds.
AK079618 - Mus musculus adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330078K03 product:microtubule-associated protein 2, full insert sequence.
AK162597 - Mus musculus 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630046H20 product:unclassifiable, full insert sequence.
AK046341 - Mus musculus adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230372P07 product:microtubule-associated protein 2, full insert sequence.
AK086484 - Mus musculus 15 days embryo head cDNA, RIKEN full-length enriched library, clone:D930031J16 product:microtubule-associated protein 2, full insert sequence.
M21041 - Mouse microtubule-associated protein 2 (MAP2) mRNA, complete cds.
AK141458 - Mus musculus 12 days embryo spinal cord cDNA, RIKEN full-length enriched library, clone:C530026F16 product:microtubule-associated protein 2, full insert sequence.
BC048781 - Mus musculus microtubule-associated protein 2, mRNA (cDNA clone IMAGE:6466695), complete cds.
BC051410 - Mus musculus microtubule-associated protein 2, mRNA (cDNA clone IMAGE:6490760), complete cds.
AK162828 - Mus musculus adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230019N16 product:microtubule-associated protein 2, full insert sequence.
AK042880 - Mus musculus 7 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:A730034C02 product:microtubule-associated protein 2, full insert sequence.
AK164828 - Mus musculus 15 days embryo head cDNA, RIKEN full-length enriched library, clone:D930004G16 product:microtubule-associated protein 2, full insert sequence.
AK039532 - Mus musculus adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330055K22 product:microtubule-associated protein 2 (fragment) homolog [Rattus norvegicus], full insert sequence.

-  Biochemical and Signaling Pathways
  BioCarta from NCI Cancer Genome Anatomy Project
m_akapCentrosomePathway - Protein Kinase A at the Centrosome

-  Other Names for This Gene
  Alternate Gene Symbols: Mtap2, NM_001039934, Q3TLQ0, Q3TLQ0_MOUSE, uc007bhw.1, uc007bhw.2
UCSC ID: uc007bhw.2
RefSeq Accession: NM_001039934
Protein: Q3TLQ0 CCDS: CCDS15020.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.