Mouse Gene Angptl1 (ENSMUST00000027885.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus angiopoietin-like 1 (Angptl1), mRNA. (from RefSeq NM_028333)
Gencode Transcript: ENSMUST00000027885.7
Gencode Gene: ENSMUSG00000033544.6
Transcript (Including UTRs)
   Position: mm10 chr1:156,838,562-156,861,078 Size: 22,517 Total Exon Count: 5 Strand: +
Coding Region
   Position: mm10 chr1:156,844,606-156,860,602 Size: 15,997 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:156,838,562-156,861,078)mRNA (may differ from genome)Protein (490 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: ANGL1_MOUSE
DESCRIPTION: RecName: Full=Angiopoietin-related protein 1; AltName: Full=Angiopoietin-like protein 1; Flags: Precursor;
SUBCELLULAR LOCATION: Secreted (By similarity).
SIMILARITY: Contains 1 fibrinogen C-terminal domain.
SEQUENCE CAUTION: Sequence=BAB28537.1; Type=Frameshift; Positions=26;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -182.20702-0.260 Picture PostScript Text
3' UTR -80.30476-0.169 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002181 - Fibrinogen_a/b/g_C
IPR014716 - Fibrinogen_a/b/g_C_1
IPR014715 - Fibrinogen_a/b/g_C_2
IPR020837 - Fibrinogen_CS

Pfam Domains:
PF00147 - Fibrinogen beta and gamma chains, C-terminal globular domain

SCOP Domains:
56496 - Fibrinogen C-terminal domain-like

ModBase Predicted Comparative 3D Structure on Q640P2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005102 receptor binding

Biological Process:
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component:
GO:0005576 extracellular region
GO:0005615 extracellular space


-  Descriptions from all associated GenBank mRNAs
  AK142319 - Mus musculus 13 days embryo heart cDNA, RIKEN full-length enriched library, clone:D330049I06 product:angiopoietin-like 1, full insert sequence.
AK012888 - Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810039D03 product:angiopoietin-like 1, full insert sequence.
BC082563 - Mus musculus angiopoietin-like 1, mRNA (cDNA clone MGC:100363 IMAGE:30607749), complete cds.
AK027978 - Mus musculus 18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110055O21 product:weakly similar to ANGIOPOIETIN Y1 (DJ595C2.2) (ANGIOPOIETIN-RELATED PROTEIN 1 PRECURSOR) [Homo sapiens], full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: ANGL1_MOUSE, NM_028333, Q3UQL1, Q640P2, Q9CZ81, uc007ddd.1, uc007ddd.2, uc007ddd.3, uc007ddd.4
UCSC ID: uc007ddd.4
RefSeq Accession: NM_028333
Protein: Q640P2 (aka ANGL1_MOUSE)
CCDS: CCDS15397.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.