Mouse Gene Tmem63a (ENSMUST00000027800.14) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus transmembrane protein 63a (Tmem63a), mRNA. (from RefSeq NM_144794)
Gencode Transcript: ENSMUST00000027800.14
Gencode Gene: ENSMUSG00000026519.16
Transcript (Including UTRs)
Position: mm10 chr1:180,942,459-180,975,112 Size: 32,654 Total Exon Count: 23 Strand: +
Coding Region
Position: mm10 chr1:180,946,580-180,974,336 Size: 27,757 Coding Exon Count: 22
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TM63A_MOUSE
DESCRIPTION: RecName: Full=Transmembrane protein 63A;
SUBCELLULAR LOCATION: Lysosome membrane; Multi-pass membrane protein (By similarity).SIMILARITY: Belongs to the SPO75/TMEM63 family.SEQUENCE CAUTION: Sequence=BAD32305.1; Type=Erroneous initiation; Sequence=BAE41880.1; Type=Erroneous termination; Positions=774; Note=Translated as Tyr;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR003864 - DUF221
IPR012677 - Nucleotide-bd_a/b_plait
IPR026957 - TMEM63
Pfam Domains: PF02714 - Calcium-dependent channel, 7TM region, putative phosphate
PF13967 - Late exocytosis, associated with Golgi transport
PF14703 - Cytosolic domain of 10TM putative phosphate transporter
SCOP Domains: 54928 - RNA-binding domain, RBD
ModBase Predicted Comparative 3D Structure on Q91YT8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF202370 - JP 2014500723-A/9873: Polycomb-Associated Non-Coding RNAs.LF193059 - JP 2014500723-A/562: Polycomb-Associated Non-Coding RNAs.AK144899 - Mus musculus lung RCB-0558 LLC cDNA, RIKEN full-length enriched library, clone:G730050I17 product:hypothetical protein, full insert sequence.AK170559 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630107N20 product:hypothetical protein, full insert sequence.BC019442 - Mus musculus transmembrane protein 63a, mRNA (cDNA clone MGC:25803 IMAGE:4036849), complete cds.AK049360 - Mus musculus ES cells cDNA, RIKEN full-length enriched library, clone:C330028B17 product:hypothetical protein, full insert sequence.AK173027 - Mus musculus mRNA for mKIAA0792 protein.BC014795 - Mus musculus transmembrane protein 63a, mRNA (cDNA clone MGC:11687 IMAGE:3961992), complete cds.LF220463 - JP 2014500723-A/27966: Polycomb-Associated Non-Coding RNAs.LF193060 - JP 2014500723-A/563: Polycomb-Associated Non-Coding RNAs.AK215121 - Mus musculus cDNA, clone:Y2G0134A14, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027800, based on BLAT search.LF220468 - JP 2014500723-A/27971: Polycomb-Associated Non-Coding RNAs.LF220470 - JP 2014500723-A/27973: Polycomb-Associated Non-Coding RNAs.LF220471 - JP 2014500723-A/27974: Polycomb-Associated Non-Coding RNAs.LF220473 - JP 2014500723-A/27976: Polycomb-Associated Non-Coding RNAs.LF220474 - JP 2014500723-A/27977: Polycomb-Associated Non-Coding RNAs.AK218532 - Mus musculus cDNA, clone:Y2G0145H17, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027800, based on BLAT search.AK219713 - Mus musculus cDNA, clone:Y2G0149F18, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027800, based on BLAT search.AK211483 - Mus musculus cDNA, clone:Y2G0121O11, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027800, based on BLAT search.LF220480 - JP 2014500723-A/27983: Polycomb-Associated Non-Coding RNAs.LF220481 - JP 2014500723-A/27984: Polycomb-Associated Non-Coding RNAs.AK196306 - Mus musculus cDNA, clone:Y1G0121H06, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027800, based on BLAT search.AK205689 - Mus musculus cDNA, clone:Y2G0102H16, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027800, based on BLAT search.MA437947 - JP 2018138019-A/9873: Polycomb-Associated Non-Coding RNAs.MA428636 - JP 2018138019-A/562: Polycomb-Associated Non-Coding RNAs.MA456040 - JP 2018138019-A/27966: Polycomb-Associated Non-Coding RNAs.MA428637 - JP 2018138019-A/563: Polycomb-Associated Non-Coding RNAs.MA456045 - JP 2018138019-A/27971: Polycomb-Associated Non-Coding RNAs.MA456047 - JP 2018138019-A/27973: Polycomb-Associated Non-Coding RNAs.MA456048 - JP 2018138019-A/27974: Polycomb-Associated Non-Coding RNAs.MA456050 - JP 2018138019-A/27976: Polycomb-Associated Non-Coding RNAs.MA456051 - JP 2018138019-A/27977: Polycomb-Associated Non-Coding RNAs.MA456057 - JP 2018138019-A/27983: Polycomb-Associated Non-Coding RNAs.MA456058 - JP 2018138019-A/27984: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: Kiaa0792, NM_144794, Q3TCS5, Q69ZZ1, Q91YT8, TM63A_MOUSE, uc007dwx.1, uc007dwx.2UCSC ID: uc007dwx.2RefSeq Accession: NM_144794
Protein: Q91YT8
(aka TM63A_MOUSE)
CCDS: CCDS15578.1
Gene Model Information
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Methods, Credits, and Use Restrictions
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