Mouse Gene Cd63 (ENSMUST00000219317.1) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Cd63 (from geneSymbol)
Gencode Transcript: ENSMUST00000219317.1
Gencode Gene: ENSMUSG00000025351.14
Transcript (Including UTRs)
   Position: mm10 chr10:128,900,989-128,912,822 Size: 11,834 Total Exon Count: 9 Strand: +
Coding Region
   Position: mm10 chr10:128,910,406-128,912,740 Size: 2,335 Coding Exon Count: 7 

Page IndexSequence and LinksPrimersCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:128,900,989-128,912,822)mRNA (may differ from genome)Protein (238 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsMGIPubMed
SOURCEUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -104.60310-0.337 Picture PostScript Text
3' UTR -15.1082-0.184 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000301 - Tetraspanin
IPR018499 - Tetraspanin/Peripherin
IPR018503 - Tetraspanin_CS
IPR008952 - Tetraspanin_EC2

Pfam Domains:
PF00335 - Tetraspanin family

SCOP Domains:
48652 - Tetraspanin

ModBase Predicted Comparative 3D Structure on Q549D0
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0002092 positive regulation of receptor internalization
GO:0007160 cell-matrix adhesion
GO:0016477 cell migration
GO:0034613 cellular protein localization
GO:0035646 endosome to melanosome transport
GO:0043473 pigmentation
GO:0048757 pigment granule maturation
GO:0050931 pigment cell differentiation
GO:1900746 regulation of vascular endothelial growth factor signaling pathway
GO:1901379 regulation of potassium ion transmembrane transport
GO:2001046 positive regulation of integrin-mediated signaling pathway

Cellular Component:
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031226 intrinsic component of plasma membrane
GO:0031902 late endosome membrane
GO:0031904 endosome lumen
GO:0032585 multivesicular body membrane
GO:0070062 extracellular exosome
GO:0097487 multivesicular body, internal vesicle


-  Descriptions from all associated GenBank mRNAs
  LF198329 - JP 2014500723-A/5832: Polycomb-Associated Non-Coding RNAs.
BC083161 - Mus musculus CD63 antigen, mRNA (cDNA clone MGC:103180 IMAGE:6530532), complete cds.
AK150647 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830013C09 product:Cd63 antigen, full insert sequence.
AK170344 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630049B10 product:Cd63 antigen, full insert sequence.
AK146618 - Mus musculus 17 days pregnant adult female amnion cDNA, RIKEN full-length enriched library, clone:I920035F01 product:Cd63 antigen, full insert sequence.
AK151702 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830034K07 product:Cd63 antigen, full insert sequence.
AK152372 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830067F14 product:Cd63 antigen, full insert sequence.
AK159875 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420036E06 product:Cd63 antigen, full insert sequence.
AK163785 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130024F04 product:Cd63 antigen, full insert sequence.
AK166543 - Mus musculus cDNA, RIKEN full-length enriched library, clone:I0C0012L21 product:Cd63 antigen, full insert sequence.
AK152072 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830047B21 product:Cd63 antigen, full insert sequence.
AK166766 - Mus musculus blastocyst blastocyst cDNA, RIKEN full-length enriched library, clone:I1C0010A18 product:Cd63 antigen, full insert sequence.
BC008108 - Mus musculus CD63 antigen, mRNA (cDNA clone MGC:7123 IMAGE:3157993), complete cds.
BC012212 - Mus musculus CD63 antigen, mRNA (cDNA clone MGC:6087 IMAGE:3157993), complete cds.
AK166373 - Mus musculus mammary gland RCB-0527 Jyg-MC(B) cDNA, RIKEN full-length enriched library, clone:G930003J03 product:Cd63 antigen, full insert sequence.
D16432 - Mus musculus mRNA for CD63/ME491, complete cds.
AK028220 - Mus musculus 10, 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2810024G22 product:Cd63 antigen, full insert sequence.
AK151963 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:I830044B09 product:Cd63 antigen, full insert sequence.
BC089543 - Mus musculus CD63 antigen, mRNA (cDNA clone IMAGE:30284264).
AF159427 - Mus musculus tetraspanin membrane protein CD63 mRNA, complete cds.
LF225549 - JP 2014500723-A/33052: Polycomb-Associated Non-Coding RNAs.
CT010179 - Mus musculus full open reading frame cDNA clone RZPDo836C0250D for gene Cd63, Cd63 antigen; complete cds, incl. stopcodon.
LF255111 - JP 2014500723-A/62614: Polycomb-Associated Non-Coding RNAs.
LF225551 - JP 2014500723-A/33054: Polycomb-Associated Non-Coding RNAs.
AK208438 - Mus musculus cDNA, clone:Y2G0111F12, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK178582 - Mus musculus cDNA, clone:Y0G0107E03, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK188949 - Mus musculus cDNA, clone:Y0G0147B06, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK216882 - Mus musculus cDNA, clone:Y2G0139O06, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK210314 - Mus musculus cDNA, clone:Y2G0118A02, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK182243 - Mus musculus cDNA, clone:Y0G0121F11, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
LF225552 - JP 2014500723-A/33055: Polycomb-Associated Non-Coding RNAs.
LF255112 - JP 2014500723-A/62615: Polycomb-Associated Non-Coding RNAs.
LF225553 - JP 2014500723-A/33056: Polycomb-Associated Non-Coding RNAs.
LF225554 - JP 2014500723-A/33057: Polycomb-Associated Non-Coding RNAs.
LF255113 - JP 2014500723-A/62616: Polycomb-Associated Non-Coding RNAs.
LF225555 - JP 2014500723-A/33058: Polycomb-Associated Non-Coding RNAs.
AK178060 - Mus musculus cDNA, clone:Y0G0105E11, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK188607 - Mus musculus cDNA, clone:Y0G0145N16, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK211715 - Mus musculus cDNA, clone:Y2G0122K02, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
LF255114 - JP 2014500723-A/62617: Polycomb-Associated Non-Coding RNAs.
AK184072 - Mus musculus cDNA, clone:Y0G0128H13, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK184717 - Mus musculus cDNA, clone:Y0G0131E14, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
AK180551 - Mus musculus cDNA, clone:Y0G0114M21, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000026407, based on BLAT search.
LF225556 - JP 2014500723-A/33059: Polycomb-Associated Non-Coding RNAs.
LF225557 - JP 2014500723-A/33060: Polycomb-Associated Non-Coding RNAs.
MA433906 - JP 2018138019-A/5832: Polycomb-Associated Non-Coding RNAs.
MA461126 - JP 2018138019-A/33052: Polycomb-Associated Non-Coding RNAs.
MA461128 - JP 2018138019-A/33054: Polycomb-Associated Non-Coding RNAs.
MA461129 - JP 2018138019-A/33055: Polycomb-Associated Non-Coding RNAs.
MA461130 - JP 2018138019-A/33056: Polycomb-Associated Non-Coding RNAs.
MA461131 - JP 2018138019-A/33057: Polycomb-Associated Non-Coding RNAs.
MA461132 - JP 2018138019-A/33058: Polycomb-Associated Non-Coding RNAs.
MA461133 - JP 2018138019-A/33059: Polycomb-Associated Non-Coding RNAs.
MA461134 - JP 2018138019-A/33060: Polycomb-Associated Non-Coding RNAs.
MA490688 - JP 2018138019-A/62614: Polycomb-Associated Non-Coding RNAs.
MA490689 - JP 2018138019-A/62615: Polycomb-Associated Non-Coding RNAs.
MA490690 - JP 2018138019-A/62616: Polycomb-Associated Non-Coding RNAs.
MA490691 - JP 2018138019-A/62617: Polycomb-Associated Non-Coding RNAs.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
mmu04142 - Lysosome

-  Other Names for This Gene
  Alternate Gene Symbols: BC083161, mCG_18675, Q549D0, Q549D0_MOUSE, uc007hou.1, uc007hou.2, uc007hou.3
UCSC ID: uc007hou.3
RefSeq Accession: NM_001042580
Protein: Q549D0 CCDS: CCDS24297.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.