Mouse Gene 0610010K14Rik (ENSMUST00000108578.8) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus RIKEN cDNA 0610010K14 gene (0610010K14Rik), transcript variant 2, mRNA. (from RefSeq NM_145758)
Gencode Transcript: ENSMUST00000108578.8
Gencode Gene: ENSMUSG00000020831.18
Transcript (Including UTRs)
   Position: mm10 chr11:70,235,206-70,237,914 Size: 2,709 Total Exon Count: 6 Strand: -
Coding Region
   Position: mm10 chr11:70,235,460-70,237,804 Size: 2,345 Coding Exon Count: 6 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:70,235,206-70,237,914)mRNA (may differ from genome)Protein (171 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: BAP18_MOUSE
DESCRIPTION: RecName: Full=Chromatin complexes subunit BAP18; AltName: Full=BPTF-associated protein of 18 kDa;
FUNCTION: Component of chromatin complexes such as the MLL1/MLL and NURF complexes (By similarity).
SUBUNIT: Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Component of the nucleosome-remodeling factor (NURF) complex (By similarity).
SUBCELLULAR LOCATION: Nucleus (Potential).
SIMILARITY: Contains 1 SANT domain.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -58.00110-0.527 Picture PostScript Text
3' UTR -68.40254-0.269 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR009057 - Homeodomain-like
IPR001005 - SANT/Myb

SCOP Domains:
46689 - Homeodomain-like

ModBase Predicted Comparative 3D Structure on Q9DCT6
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function
GO:0003677 DNA binding

Biological Process:
GO:0006325 chromatin organization
GO:0008150 biological_process

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0016589 NURF complex
GO:0071339 MLL1 complex


-  Descriptions from all associated GenBank mRNAs
  LF198636 - JP 2014500723-A/6139: Polycomb-Associated Non-Coding RNAs.
BC055357 - Mus musculus RIKEN cDNA 0610010K14 gene, mRNA (cDNA clone MGC:67826 IMAGE:5325264), complete cds.
BC012258 - Mus musculus cDNA clone IMAGE:4208190, **** WARNING: chimeric clone ****.
AK169173 - Mus musculus 17 days embryo heart cDNA, RIKEN full-length enriched library, clone:I920087J22 product:hypothetical protein, full insert sequence.
AK003842 - Mus musculus 18-day embryo whole body cDNA, RIKEN full-length enriched library, clone:1110020A23 product:hypothetical protein, full insert sequence.
AK170380 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630101K22 product:hypothetical Homeodomain-like containing protein, full insert sequence.
AK002491 - Mus musculus adult male kidney cDNA, RIKEN full-length enriched library, clone:0610010K14 product:hypothetical Homeodomain-like structure containing protein, full insert sequence.
AL355701 - Mus musculus EST from clone 643475, full insert.
AK208696 - Mus musculus cDNA, clone:Y2G0112H11, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000068478, based on BLAT search.
LF228572 - JP 2014500723-A/36075: Polycomb-Associated Non-Coding RNAs.
BC037772 - Mus musculus, clone IMAGE:1530626, mRNA.
MA434213 - JP 2018138019-A/6139: Polycomb-Associated Non-Coding RNAs.
MA464149 - JP 2018138019-A/36075: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: Bap18, BAP18_MOUSE, NM_145758, Q3TFE6, Q7TMP3, Q9D183, Q9DCT6, uc007juh.1, uc007juh.2, uc007juh.3
UCSC ID: uc007juh.3
RefSeq Accession: NM_145758
Protein: Q9DCT6 (aka BAP18_MOUSE)
CCDS: CCDS48835.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.