Mouse Gene Mrps7 (ENSMUST00000058109.8) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus mitchondrial ribosomal protein S7 (Mrps7), mRNA. (from RefSeq NM_025305)
Gencode Transcript: ENSMUST00000058109.8
Gencode Gene: ENSMUSG00000046756.10
Transcript (Including UTRs)
   Position: mm10 chr11:115,603,925-115,608,036 Size: 4,112 Total Exon Count: 5 Strand: +
Coding Region
   Position: mm10 chr11:115,604,161-115,607,039 Size: 2,879 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:115,603,925-115,608,036)mRNA (may differ from genome)Protein (242 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedReactomeSOURCEUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: RT07_MOUSE
DESCRIPTION: RecName: Full=28S ribosomal protein S7, mitochondrial; Short=MRP-S7; Short=S7mt; Flags: Precursor;
SUBUNIT: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins (By similarity).
SUBCELLULAR LOCATION: Mitochondrion (By similarity).
SIMILARITY: Belongs to the ribosomal protein S7P family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -130.10236-0.551 Picture PostScript Text
3' UTR -350.70997-0.352 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000235 - Ribosomal_S5/S7
IPR023798 - Ribosomal_S7_dom

Pfam Domains:
PF00177 - Ribosomal protein S7p/S5e

SCOP Domains:
47973 - Ribosomal protein S7

ModBase Predicted Comparative 3D Structure on Q80X85
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserGenome BrowserNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsemblEnsemblWormBase 
Protein SequenceProtein Sequence Protein SequenceProtein Sequence 
AlignmentAlignment AlignmentAlignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding

Biological Process:
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
GO:0032543 mitochondrial translation

Cellular Component:
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome


-  Descriptions from all associated GenBank mRNAs
  AK046222 - Mus musculus adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230354I04 product:unclassifiable, full insert sequence.
LF198983 - JP 2014500723-A/6486: Polycomb-Associated Non-Coding RNAs.
AK131937 - Mus musculus ES cells cDNA, RIKEN full-length enriched library, clone:2410008G21 product:mitchondrial ribosomal protein S7, full insert sequence.
AK012225 - Mus musculus 11 days embryo whole body cDNA, RIKEN full-length enriched library, clone:2700008O11 product:mitchondrial ribosomal protein S7, full insert sequence.
BC049636 - Mus musculus mitchondrial ribosomal protein S7, mRNA (cDNA clone MGC:58388 IMAGE:6532964), complete cds.
AK162024 - Mus musculus 12 days embryo female mullerian duct includes surrounding region cDNA, RIKEN full-length enriched library, clone:6820413L12 product:mitchondrial ribosomal protein S7, full insert sequence.
AK009251 - Mus musculus adult male tongue cDNA, RIKEN full-length enriched library, clone:2310009G03 product:mitchondrial ribosomal protein S7, full insert sequence.
Y10968 - M.musculus E800 mRNA.
MA434560 - JP 2018138019-A/6486: Polycomb-Associated Non-Coding RNAs.
AB341708 - Mus musculus non-coding RNA, oocyte_clustered_small_RNA6909, complete sequence.
LF231398 - JP 2014500723-A/38901: Polycomb-Associated Non-Coding RNAs.
MA466975 - JP 2018138019-A/38901: Polycomb-Associated Non-Coding RNAs.
AK201654 - Mus musculus cDNA, clone:Y1G0138O21, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000065006, based on BLAT search.
AK189027 - Mus musculus cDNA, clone:Y0G0147H15, strand:unspecified.
LF231400 - JP 2014500723-A/38903: Polycomb-Associated Non-Coding RNAs.
LF231402 - JP 2014500723-A/38905: Polycomb-Associated Non-Coding RNAs.
MA466977 - JP 2018138019-A/38903: Polycomb-Associated Non-Coding RNAs.
MA466979 - JP 2018138019-A/38905: Polycomb-Associated Non-Coding RNAs.

-  Biochemical and Signaling Pathways
  Reactome (by CSHL, EBI, and GO)

Protein Q80X85 (Reactome details) participates in the following event(s):

R-MMU-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits
R-MMU-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP
R-MMU-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA
R-MMU-5419281 MRRF binds 55S ribosome:mRNA:tRNA
R-MMU-5419276 Mitochondrial translation termination
R-MMU-5368287 Mitochondrial translation
R-MMU-5389840 Mitochondrial translation elongation
R-MMU-72766 Translation
R-MMU-392499 Metabolism of proteins

-  Other Names for This Gene
  Alternate Gene Symbols: NM_025305, Q3TSI9, Q80X85, Q9CV71, RT07_MOUSE, uc007mia.1, uc007mia.2
UCSC ID: uc007mia.2
RefSeq Accession: NM_025305
Protein: Q80X85 (aka RT07_MOUSE)
CCDS: CCDS25642.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.