Mouse Gene Slc16a3 (ENSMUST00000070653.12) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus solute carrier family 16 (monocarboxylic acid transporters), member 3 (Slc16a3), mRNA. (from RefSeq NM_030696)
Gencode Transcript: ENSMUST00000070653.12
Gencode Gene: ENSMUSG00000025161.16
Transcript (Including UTRs)
   Position: mm10 chr11:120,948,480-120,958,775 Size: 10,296 Total Exon Count: 6 Strand: +
Coding Region
   Position: mm10 chr11:120,955,247-120,958,132 Size: 2,886 Coding Exon Count: 4 

Page IndexSequence and LinksPrimersCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-19

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:120,948,480-120,958,775)mRNA (may differ from genome)Protein (470 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -71.80216-0.332 Picture PostScript Text
3' UTR -252.90643-0.393 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011701 - MFS
IPR020846 - MFS_dom
IPR016196 - MFS_dom_general_subst_transpt
IPR004743 - Monocarb_transpt

Pfam Domains:
PF07690 - Major Facilitator Superfamily

SCOP Domains:
53067 - Actin-like ATPase domain
103473 - MFS general substrate transporter

ModBase Predicted Comparative 3D Structure on Q3UDP9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0008028 monocarboxylic acid transmembrane transporter activity
GO:0015129 lactate transmembrane transporter activity

Biological Process:
GO:0015718 monocarboxylic acid transport
GO:0035879 plasma membrane lactate transport
GO:0055085 transmembrane transport

Cellular Component:
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane


-  Descriptions from all associated GenBank mRNAs
  BC046525 - Mus musculus solute carrier family 16 (monocarboxylic acid transporters), member 3, mRNA (cDNA clone MGC:51666 IMAGE:5319754), complete cds.
AK149707 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:G530011J24 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AK149983 - Mus musculus bone marrow macrophage cDNA, RIKEN full-length enriched library, clone:G530112G22 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AK141381 - Mus musculus 7 days embryo whole body cDNA, RIKEN full-length enriched library, clone:C430044D20 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AK171260 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630318M11 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AK166048 - Mus musculus lung RCB-0558 LLC cDNA, RIKEN full-length enriched library, clone:G730030P11 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AK169917 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630004E21 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AK165596 - Mus musculus RCB-0035 WEHI-3 cDNA, RIKEN full-length enriched library, clone:G430039A17 product:solute carrier family 16 (monocarboxylic acid transporters), member 3, full insert sequence.
AF178954 - Mus musculus monocarboxylate transporter 4 mRNA, complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: mCG_2155, NM_030696, Q3UDP9, Q3UDP9_MOUSE, RP23-378G22.1-001, uc007muw.1, uc007muw.2
UCSC ID: uc007muw.2
RefSeq Accession: NM_030696
Protein: Q3UDP9 CCDS: CCDS25761.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.