The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O08797
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0002020 protease binding GO:0004867 serine-type endopeptidase inhibitor activity GO:0005515 protein binding GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Biological Process: GO:0001913 T cell mediated cytotoxicity GO:0002438 acute inflammatory response to antigenic stimulus GO:0006915 apoptotic process GO:0006955 immune response GO:0009617 response to bacterium GO:0010628 positive regulation of gene expression GO:0010951 negative regulation of endopeptidase activity GO:0033668 negative regulation by symbiont of host apoptotic process GO:0042270 protection from natural killer cell mediated cytotoxicity GO:0042742 defense response to bacterium GO:0043066 negative regulation of apoptotic process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0070233 negative regulation of T cell apoptotic process