ID:DDX4_MOUSE DESCRIPTION: RecName: Full=Probable ATP-dependent RNA helicase DDX4; EC=3.6.4.13; AltName: Full=DEAD box protein 4; AltName: Full=Mvh; AltName: Full=Vasa homolog; FUNCTION: May play a role in germ cell development. May play a role in sperm motility (By similarity). CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. SUBUNIT: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. N-terminus interacts with RANBP9. Interacts with PIWIL2 and MAEL. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, perinuclear region. TISSUE SPECIFICITY: Testis. DEVELOPMENTAL STAGE: Expressed in spermatogenic cells from the spermatocyte stage to the round spermatid stage. SIMILARITY: Belongs to the DEAD box helicase family. DDX4/VASA subfamily. SIMILARITY: Contains 1 helicase ATP-binding domain. SIMILARITY: Contains 1 helicase C-terminal domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q61496
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
