Mouse Gene Gzmc (ENSMUST00000015585.3) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus granzyme C (Gzmc), mRNA. (from RefSeq NM_010371) RefSeq Summary (NM_010371): This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product, expressed by activated T cells, may induce apoptosis of target cells. This gene is present in a gene cluster with other members of the granzyme subfamily on chromosome 14. [provided by RefSeq, Sep 2015]. Gencode Transcript: ENSMUST00000015585.3 Gencode Gene: ENSMUSG00000079186.3 Transcript (Including UTRs) Position: mm10 chr14:56,231,441-56,234,656 Size: 3,216 Total Exon Count: 5 Strand: - Coding Region Position: mm10 chr14:56,231,514-56,234,582 Size: 3,069 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q0VB76
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.