Mouse Gene Kcnrg (ENSMUST00000051184.9) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Mus musculus potassium channel regulator (Kcnrg), transcript variant 1, mRNA. (from RefSeq NM_001039105)
Gencode Transcript: ENSMUST00000051184.9
Gencode Gene: ENSMUSG00000046168.9
Transcript (Including UTRs)
Position: mm10 chr14:61,607,482-61,612,826 Size: 5,345 Total Exon Count: 2 Strand: +
Coding Region
Position: mm10 chr14:61,607,513-61,611,886 Size: 4,374 Coding Exon Count: 2
Data last updated at UCSC: 2019-09-19
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: KCNRG_MOUSE
DESCRIPTION: RecName: Full=Potassium channel regulatory protein; Short=Potassium channel regulator; AltName: Full=Protein CLLD4;
FUNCTION: Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes (By similarity).SUBCELLULAR LOCATION: Endoplasmic reticulum (By similarity).SIMILARITY: Contains 1 BTB (POZ) domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000210 - BTB/POZ-like
IPR011333 - BTB/POZ_fold
IPR003131 - T1-type_BTB
Pfam Domains: PF02214 - BTB/POZ domain
SCOP Domains: 54695 - POZ domain
ModBase Predicted Comparative 3D Structure on Q2TUM3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0042802 identical protein binding
Biological Process: GO:0051260 protein homooligomerization
GO:1902260 negative regulation of delayed rectifier potassium channel activity
Cellular Component: GO:0005783 endoplasmic reticulum
Descriptions from all associated GenBank mRNAs
LF205015 - JP 2014500723-A/12518: Polycomb-Associated Non-Coding RNAs.LF200009 - JP 2014500723-A/7512: Polycomb-Associated Non-Coding RNAs.AK053138 - Mus musculus 0 day neonate lung cDNA, RIKEN full-length enriched library, clone:E030012H22 product:hypothetical BTB/POZ domain/K+ channel tetramerisation domain containing protein, full insert sequence.AY491736 - Mus musculus CLLD4-like protein 29 kDa isoform mRNA, complete cds, alternatively spliced.AY491737 - Mus musculus CLLD4-like protein 22 kDa isoform mRNA, complete cds, alternatively spliced.BC147091 - Mus musculus potassium channel regulator, mRNA (cDNA clone MGC:182246 IMAGE:9056140), complete cds.BC147092 - Mus musculus potassium channel regulator, mRNA (cDNA clone MGC:182235 IMAGE:9056129), complete cds.BC171997 - Mus musculus potassium channel regulator, mRNA (cDNA clone MGC:198702 IMAGE:9054283), complete cds.LF241312 - JP 2014500723-A/48815: Polycomb-Associated Non-Coding RNAs.BC061223 - Mus musculus potassium channel regulator, mRNA (cDNA clone IMAGE:30297072), with apparent retained intron.MA440592 - JP 2018138019-A/12518: Polycomb-Associated Non-Coding RNAs.MA435586 - JP 2018138019-A/7512: Polycomb-Associated Non-Coding RNAs.MA476889 - JP 2018138019-A/48815: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: B2RV87, B7ZWD9, Clld4, KCNRG_MOUSE, NM_001039105, Q2TUM3, Q6P8J6, Q8C6V1, uc007uge.1, uc007uge.2, uc007uge.3UCSC ID: uc007uge.3RefSeq Accession: NM_001039105
Protein: Q2TUM3
(aka KCNRG_MOUSE)
CCDS: CCDS27187.1
Gene Model Information
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.